However, Professor Lu Jiahai of Sun Yat-sen University and his graduate team changed their thinking, and instead of starting with exogenous stem cells, they devoted themselves to promoting the growth and recovery of their own skin stem cells. After years of research, they finally found that applying some small molecules with active peptides to specific parts can stimulate "awakening" or nourish epidermal or dermal stem cells. The role of small molecular bioactive peptides in awakening epidermal stem cells is:
1. At the epidermal level, factors affecting the activity and growth of keratinocytes stimulate the migration and epithelization of keratinocytes, stimulate the differentiation and correction of keratinocytes, and strongly promote the repair and healing of epidermis.
2. Dermal layer: Stimulate the activity of fibroblasts, enhance the contraction and structure of extracellular matrix, provide skin nutrition, and promote skin wound healing and functional regeneration.
3. On the whole skin level: enhance the resistance to environmental invasion, ultraviolet rays, pollutants, irritants, allergens and inflammatory cells, consolidate and enhance skin tension, enhance skin elasticity, stimulate scar tissue regression, reduce scar formation and delay skin aging.
The main mechanisms are: ① promoting the proliferation, division and differentiation of epidermal and dermal cells (especially fibroblasts, epithelial cells and endothelial cells), increasing the number of new cells, thickening the skin and gradually restoring the normal structure and physiological function of the skin; ② Promote the formation of collagen fiber, reticular fiber and elastic fiber, regulate the secretion of collagen and mucopolysaccharide, maintain the moisture content and electrolyte metabolism of skin tissue, improve the water shortage of atrophic skin and moisturize skin tissue; ③ Promote the formation of new capillaries in skin tissue through the action on vascular endothelial cells.
Professor Lu Jiahai and his graduate team extracted three kinds of active peptides from deep-sea fish eggs by pure physical extraction method-fish egg polypeptide stock solution (patented). The experimental study on the mechanism of its action on human epidermal stem cells and animal models shows that it has many important biological effects and physiological functions. Adding caviar polypeptide stock solution to the culture medium of human epithelial cells, fibroblasts, vascular endothelial cells and corneal cells cultured in vitro can significantly accelerate the division and proliferation of these cells; After more than seven years' practice and nearly ten thousand people's application, it was found that roe polypeptide stock solution can obviously improve unhealthy skin conditions such as wrinkles, relaxation, pigmentation, dark tone and dull complexion, and it is extremely safe. This further shows that roe polypeptide stock solution is related to the growth, division, differentiation, proliferation and migration of skin cells, which can provide skin nutrition, delay skin aging and promote skin wound repair.
Both experimental research and clinical application show that adding caviar polypeptide stock solution to beauty cosmetics can effectively interact with skin cells and exert its outstanding beauty and skin care effect, which is of great significance to improve the function of skin care products. Judging from the research trend of cosmetics, developing products from a single mechanism often cannot solve the comprehensive manifestations of cell aging, so we must develop products that can better solve the problems from all directions, levels and angles. Based on this idea, Professor Lu Jiahai's research team spent ten years trying to develop this caviar polypeptide stock solution that can meet the skin health needs.
When stem cells continuously meet the needs of the skin, the health of the skin will be guaranteed, various skin problems can be effectively prevented, and the skin can return to a younger and healthier state, truly achieving beauty from the inside out.