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What are the manifestations of abnormal liver function? What tests should I do?
According to liver function test index, liver function test indexes such as alanine aminotransferase, aspartate aminotransferase, direct bilirubin, indirect bilirubin, total bilirubin, total protein, albumin, globulin, alkaline phosphatase and glutamyl transpeptidase may increase or decrease in different degrees when liver function is abnormal; From the symptoms, abnormal liver function often leads to abnormal digestive function, which is manifested as loss of appetite, aversion to greasy food, nausea, vomiting, diarrhea or constipation. Most patients with abnormal liver function will also be accompanied by general weakness, fatigue, lethargy, discomfort in the liver area, and severe yellow urine such as brown, yellow sclera and yellow skin. Experts from Guizhou Limeikang Liver Disease Hospital suggested that when the liver function is abnormal, patients may have symptoms such as aversion to oil, nausea and pain in the liver area. If you find yourself with such symptoms, you'd better go to the hospital for examination. I hope there is nothing serious wrong with you.

Abnormal liver function generally requires the following tests:

1. Liver excretion function: sodium bromosulfophthalein (BsP) excretion test and indigo green (ICG) excretion test are commonly used.

2. Metabolic function of protein: determination of serum total protein, albumin, globulin, prealbumin, protein electrophoresis, prothrombin time and alpha-fetoprotein (AFP);

3. Lipid metabolism function: determination of serum total cholesterol, serum triglyceride, high density lipoprotein cholesterol, low density lipoprotein cholesterol, apolipoprotein, apolipoprotein and lipoprotein;

Mineral metabolism function: determination of serum iron, transferrin, ferritin and serum copper.

5. Hormone metabolic function: determination of plasma estrogen (E2) and testosterone, urine 17- ketosteroid and urine 17- hydroxysteroid.

Metabolic function of bilirubin: quantitative test of serum bilirubin, determination of direct bilirubin, indirect bilirubin, qualitative test of urinary bilirubin and determination of urinary bilirubin;

Seven, bile acid metabolic function: enzyme biochemical method to determine serum total bile acid and radioimmunoassay to determine bound bile acid;

8. Interstitial metabolic function: hyaluronic acid, laminin, fibronectin, collagen IV and its fragments, N-terminal propeptide of collagen III, C-terminal propeptide of collagen I, C-terminal propeptide of collagen I, collagen cleavage products and hydroxyproline, etc.