After face-lifting needle injection, the general face-lifting effect can be maintained for about one year, and then there is the possibility of recurrence, but the face-lifting needle can be injected again. The local adverse reactions after injection of slimming needle mainly include myasthenia gravis and the corresponding manifestations caused by the diffusion of slimming needle to adjacent muscle tissues, and these clinical manifestations are related to the injection site and the dose of slimming needle. Individual patients with thin face found fever, discomfort and fatigue after injection of botulinum toxin. Generally speaking, these clinical manifestations are short-lived and disappear naturally within a few weeks.