1, Definition, Manifestation and Incidence of Cleft Lip and Palate Cleft Lip and Palate is the most common congenital malformation in oral and maxillofacial region, with an incidence of about 1: 1000, which is caused by abnormal fusion of various embryonic processes in the face during embryonic development. Generally, the upper lip is cracked to varying degrees, the alveoli are cracked, the mouth and palate are cracked, and the alar is collapsed. Children can also be accompanied by different degrees of jaw deformities when they are mature, most of which are irregular dentition and irregular dentition.

2. Are there any other abnormalities in children with cleft lip and palate? Most patients with cleft lip and palate only show simple cleft lip and palate, and some patients with cleft lip and palate will be accompanied by other congenital malformations, because cleft lip and palate can be the manifestation of many head and neck syndromes. Therefore, children with cleft lip and palate should actively exclude abnormal development of heart and spine.

3. The therapeutic value and effect of cleft lip and palate can be said to be the most therapeutic congenital malformation. Excluding a few congenital malformations, the intelligence and growth of patients with simple cleft lip and palate are completely normal or even excellent. After receiving standardized treatment, cleft lip and palate deformity can be close to normal people, and its function has been greatly improved. I can live and work like a normal person.

4. Treatment Methods and Contents of Cleft Lip and Palate The internationally recognized treatment method for cleft lip and palate is comprehensive sequential therapy, including orderly treatment in orthodontics, surgery, psychology and nursing, which is an organic combination of various medical professions and social non-medical professions. At present, there is still a certain gap between China and developed countries in the perfection of comprehensive sequence therapy for cleft lip and palate, mainly in some non-surgical treatments, such as psychological intervention. At present, patients with cleft lip and palate must undergo three operations, including cleft lip repair, restoration of upper lip continuity and improvement of sucking language function. Surgery is usually performed at the age of 3-6 months. Repair of cleft palate, closure of cleft palate, isolation of mouth and nose, and improvement of pronunciation function are generally performed in children around 1 year old. Repair of alveolar cleft can close the oral-nasal fistula, restore the continuity of dental arch, and provide basis for orthodontic treatment.

5. Can cleft lip and palate be inherited? The pathogenic factors of cleft lip and palate are very complicated, including genetic factors and environmental factors, among which genetic factors are widely regarded as important factors, but the existing data at home and abroad are not ideal and lack of reliable and conclusive evidence. Secondly, congenital diseases affected by genetic factors are not the same as genetic diseases, and cleft lip and palate can only be regarded as congenital diseases, which are affected by polygenic genetic factors. Foreign literature reported that the heritability of cleft lip and palate was 20%.

6. At present, the present situation of cleft lip and palate treatment in China, the surgical treatment of cleft lip and palate began very early. At present, many hospitals can carry out comprehensive sequence therapy for cleft lip and palate. Surgeons engaged in this major are mainly composed of plastic surgery and oral and maxillofacial surgery. Plastic surgeons have done a lot of work in cleft lip and two-stage nose and lip repair. Because the major of plastic surgery is related to beauty, they implant the concept of plastic surgery into these surgical treatments. Maxillofacial surgeons are the main force in the treatment of cleft lip and palate in China at present. Because of their professional advantages, they can better take into account the functional problems in the treatment of cleft lip and palate. However, the treatment of cleft lip and palate is a process of synthesizing various treatment methods to obtain the best effect, which requires the cooperation of many disciplines and even non-medical majors, such as psychology, education and sociology. It is hoped that all professions can work together seamlessly to improve the treatment level of cleft lip and palate in China to a higher level, benefiting the majority of children and their families.