Hyaluronic acid from different sources has different components and can be divided into biochemical and organic synthesis. Because of its unstable structure, organic chemical sources may decompose at any time and cannot be used as oral or medical supplies. (Generally, it is only used in low-grade cosmetics) Another piece of hyaluronic acid from biochemistry can be divided into two types: enzymatic decomposition and comb extraction. Among them, comb extraction has the best effect, and there is no side effect of edema when taken orally. Generally, it is biomedical hyaluronic acid extracted by comb.