The "hidden clock" in the human body, the soul of all things, is also dominated by the rhythm of life. What is the body clock? Some people vividly compare the biological rhythm in the human body to a "hidden clock". Scientists' research has confirmed that everyone has many natural rhythms from the day of birth to the last day of life, such as physical strength, intelligence, mood, blood pressure, menstrual period and so on. People call these natural rhythms biological rhythms or life rhythms. There is a biological species in human body that determines people's sleep and awakening. According to the instructions of the brain, the biological clock regulates the functions of various organs in the whole body in a 24-hour cycle. As early as the end of 19, scientists noticed the phenomenon of "life rhythm" in organisms. At the beginning of last century, Wilhelm Fries, a German physician, and Herman Swapoda, an Austrian psychologist, uncovered the mystery through long-term clinical observation. It turns out that in the ups and downs of patients' symptoms, emotions and behaviors, there are 23 days of physical ups and downs and 28 days of emotional ups and downs. About 20 years later, after studying the test scores of hundreds of high school and university students, Professor Alfred Terchell of Innsbruch University found that human intelligence fluctuated within 33 days. Therefore, according to the periodic rhythm of physical strength, emotion and intelligence ups and downs, scientists have drawn three wavy curves of human biological rhythm, which are vividly described as a beautiful life ensemble. By the middle of the 20th century, biologists created the word "biological clock" according to the fact that living things have periodic cyclical rhythm activities. Biological clock 12 biological clock gene: Unveiling the mystery of biological clock According to experts, human beings have discovered 12 genes related to biological clock, which not only affect people's physical and mental health, but also play an important role in treating diseases. In 1980s, due to the development of molecular biology, the study of biological clock made a breakthrough. 197 1 year, British scientists discovered a special fruit fly in their research, and its biological clock was only 2 1 hour. It took scientists 14 years to find the gene that caused the abnormal biological clock of this fruit fly until 1985. This is the first time that human beings have discovered a gene related to the biological clock, and named this gene cycle-"cycle". Scientists have been trying to clone similar genes of this gene in other species, especially mammals, but they have not been successful. Cell Journal 65438-0997 published a paper. Through the study of tens of thousands of experimental mice, scientists found that the biological clock cycle of an experimental mouse is 27 hours, and located and cloned the gene with mutation in this nucleic acid, and named it "clock gene". Meanwhile, Dr. Sun Zhongsheng and others screened the genes on chromosome 17 on a large scale in order to clone breast cancer genes. They found that one of the genes showed a certain sequence similarity with the biological clock gene "cycle" of Drosophila, so it was speculated that the gene was a similar gene with the same function in mammals. Through animal experiments, they found that the "periodic" gene has a 24-hour expression rhythm, and the expression of this gene can change with the change of photoperiod. This discovery was named as one of 10 scientific and technological breakthroughs by Science magazine because it revealed the molecular biological basis of the biological clock. In recent years, the international community has attached great importance to the study of chronobiology and put forward the concepts of chronopathology, chronopharmacology and chronotherapeutics. Biological rhythm has become an important topic in clinical, preventive and basic medical research. China Academy of Sciences plans to establish an international chronobiology research base in China to promote the clinical application of chronobiology in China. Biological clock scientists have found that the human body has its own biological clock. At the same time, physiological beauticians have also confirmed that everyone's skin has a special schedule to follow with the change of physiological clock. Experts suggest that if it can be coordinated with the natural rest and rest of the skin, beauty care can play its greatest role. From 1 1 to 5: 00 in the morning, the speed of cell division is about 8 times faster than usual. The absorption rate of skin care products is very strong at this time. If you use moisturizing night cream and nutrient-rich moisturizing agent, you can achieve the best effect of skin maintenance and repair. At 6:00-7:00 in the morning, the secretion of adrenocortical hormone reached its peak, which inhibited the synthesis of protein, slowed down the regeneration, and reduced the cell regeneration activity to the lowest point. Intracellular water, slow lymphatic circulation, and some people will have eyelid edema. In order to cope with the stress on the skin during the day, such as dust and sun exposure, skin care products rich in vitamins A, C and E should be used to resist free radicals in the morning. People with swollen eyelids in the morning can use eye cream that can enhance eye circulation, decompose toxins accumulated in the eyes and tighten eye bags. From 8 am to 12 am, the skin has the best endurance, the strongest resistance and the most active secretion of skin glands. Plastic surgeons can perform surgery at this time, and they can also do facial and body hair removal, freckle removal, mole removal, eyebrow tattoo and eyeliner painting. 1 from 3 pm to 3 pm, blood pressure and hormone secretion decrease, the body gradually feels tired, and the skin is prone to fine wrinkles. Taking a nap 15 minutes can fully relax the face. At this time, the skin's ability to absorb cosmetics containing high-efficiency substances is particularly weak. If you want to make your skin look energetic, you can use some essence and moisturizing water. From 4 pm to 8 pm, with the enhancement of microcirculation, the oxygen content in the blood increases, the cardiopulmonary function is enhanced, and the pancreatic secretion is very strong, which can fully absorb nutrients and enhance the skin's absorption of beauty cosmetics. The pain of human body is reduced, which is suitable for eyebrow trimming and hair removal, and professional women are suitable for beauty salon maintenance. From 8: 00 pm to 1 1 pm, histamine secretion increases, and allergic reactions are most likely to occur at this time. Microvascular resistance is the weakest, blood pressure is reduced, and the human body is prone to edema, bleeding and inflammation, which is not suitable for plastic surgery. Man is a product of nature, and the biological laws of the human body are intrinsically related to the natural laws, so the biological laws of the human body are called biological clocks. The normal operation of biological clock is the guarantee of human health, longevity, intelligence, happiness and beauty. The physiological fluctuation of human body in a day is as follows: 1 point: At midnight, most people have slept for 3-5 hours, from sleep period-light sleep period-middle sleep period-deep sleep period, and then enter dream sleep period. At this time, I am easy to wake up/dream, and I am particularly sensitive to pain. Some diseases are easy to get worse at this time. 2 o'clock: the liver is still working. Take advantage of this quiet time of the human body to step up the production of various substances needed by the human body and remove some harmful substances from the body. At this time, the working rhythm of most organs of the human body slows down or stops working, and they are in a state of rest. 3 o'clock: rest the whole body and relax the muscles completely. At this time, the blood pressure is low, and the pulse and breathing times are few. 4 o'clock: the blood pressure is low, the blood supply to the brain is the least, the muscles are in the weakest circulation state, and the breathing is still very weak. At this time, people are prone to death. At this time, the rhythm of the whole body organs is still slowing down, but the hearing is very keen and it is easy to be awakened by tiny movements. 5 o'clock: the kidney secretes less, and the human body has experienced 3-4 "sleep cycles" (dreamless sleep and dreamless sleep constitute sleep cycles). At this time, when you wake up, you will soon enter a state of high spirits. 6 o'clock: blood pressure rises, the heart beats faster, the body temperature rises, and the secretion of adrenocortical hormone begins to increase. At this time, my body has awakened and I can't sleep well. This is the first best memory period. 7 o'clock: Adrenal cortical hormone secretion enters a climax, body temperature rises, blood flow accelerates, and immune function is strengthened. At 8 o'clock: the body enters an excited state after rest, and the liver has discharged all the toxins in the body. The brain has a strong memory, which is the second best memory period. 9 o'clock: the nerve excitability is improved, the memory is still in the best state, the disease infection rate is reduced, and it is the least sensitive to pain. At this time, the heart is working at full capacity and full of energy. 10 point: enthusiasm is high, enthusiasm will last until lunch, the human body is at its best for the first time, and the pain is easy to disappear. This is the most creative moment for introverts. They can do any job. It's a pity that it is wasted at this time. 1 1 point: The heart continues to work rhythmically, which is consistent with the positive state of mind. The human body is not easy to feel tired, and hardly feels great work pressure. 12 point: all the energy of the human body is mobilized. General mobilization, need to eat. Still sensitive to alcohol at this time. After lunch, the work in the second half of the day will be greatly affected. 13 o'clock: I feel sleepy after lunch, and the excitement period of the first stage of the day has passed. At this time, I feel a little tired. I want to have a proper rest, and it is best to take a nap for half an hour to 1 hour. Biological clock 14 o'clock: the energy fades, which is the second low tide stage in the 24-hour cycle, and the response is slow at this time. 15 o'clock: the body has improved again. At this time, the sensory organs are particularly sensitive and the human body is back on track. The gradual recovery of work ability is the most vigorous moment for extroverts to analyze and create, which can last for several hours. 16 point: the sugar in the blood increases, but it will soon drop again. Doctors call this process "postprandial diabetes". 17 o'clock: the working effect is higher, the sense of smell and taste are in the most sensitive period, and the hearing is in the second climax of the day. It is better to start exercising at this time than in the morning. 18 point: Physical strength and endurance of physical activity reach the peak in one day, and the desire to exercise more rises. At this time, the pain has dropped again, and athletes should work harder at this time to achieve good sports and training results. 19 point: when blood pressure rises, psychological stability drops to the lowest point, and the spirit is the most unstable and easily excited. Small things can also cause quarrels. 20 o'clock: All the food and water of the day have been reserved, and the weight is the heaviest. The response is extremely quick and agile, the driver is in the best state, and it is not easy to have an accident. 2 1 point: memory is particularly good, and it is the best time of the day (the fourth and most efficient time) before going to bed. 22 o'clock: body temperature begins to drop, drowsiness drops, immune function is enhanced, and white blood cells in the blood increase. Breathing slows down, pulse and heartbeat decrease, and hormone secretion level decreases. Most functions in the body tend to be low. At 23 o'clock, the human body is ready to rest and the cell repair work begins. 0 o'clock: The body begins the heaviest work, replacing dead cells and establishing new cells to prepare for the next day.

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