Let the purchase price be x, which is derived from the meaning of the question:

x+50%x=600，

1.5x=600，

1.5x÷ 1.5 = 600÷ 1.5，

x = 400

600×75%=450 yuan;

450>400;

450-400=50 (yuan);

Answer: The clothing store made a profit, and it made a profit in 50 yuan.