The main components of face-lifting needle are botulinum toxin and hyaluronic acid. If there is vitiligo on the face, subcutaneous injection of face-lifting needle in vitiligo, mainly to the muscle layer of the face, promotes the contraction of hypertrophic masseter muscle, especially botulinum toxin, which has no obvious irritation to the skin and may cause redness at the eye of the needle, and has little effect on vitiligo.