Purple liquid medicine (containing 1% methyl violet) is a kind of disinfectant, which has a good bactericidal effect, has no irritation to tissues, and can condense with mucous membranes and skin surfaces to form a protective film, which plays a role in convergence. Can be used for superficial wounds, ulcers and skin infections, such as small area burns, eczema, herpes, pharyngolaryngitis, thrush, etc.
Let me introduce some points for attention in treatment:
Gentian violet, whose 1 ~ 2% solution is commonly known as purple liquid medicine, is a familiar external medicine. Gentiana Violet is an alkaline cationic dye, which has antibacterial effect because its cation can combine with carboxyl group of bacterial protein and affect its metabolism. It can inhibit gram-positive bacteria, especially staphylococcus and diphtheria, and has a good antibacterial effect on Candida albicans. It has strong bactericidal power, no irritation to tissues and no toxic and side effects.
External use can treat wound infection and ulcer of skin and mucosa, mild scald, oral herpes, ulcerative pharyngitis, thrush, fungal vaginitis, vulvitis, etc. Applying 1 ~ 2% water solution or alcohol solution to the affected skin can prevent bacterial infection and extravasation of local tissue fluid. It can also combine with necrotic tissue to form a protective film, which has astringent effect, and can be used for treating pinworm disease by oral administration.
When gentian violet is used externally, if the wound has suppurated, it is not appropriate to stick it again. Because gentian violet can scab the wound, it looks clean, but bacteria are still multiplying under dry hardness. Under the protection of scabbed skin, bacteria may continue to spread and invade deeply, aggravating the condition. Therefore, gentian violet should not be used for suppurative wounds, and doctors should be asked to clean the wounds and take comprehensive treatment measures.
Purple liquid medicine is a commonly used disinfectant for skin and mucosa in clinic, which has strong bactericidal and astringent effects, but improper use will also produce many side effects, especially for infants.
The toxic and side effects of purple liquid medicine are usually manifested as systemic reaction and local reaction. The former can make the baby fidgety, irritable, crying and restless at night, and in severe cases, salivation, hoarseness, dysphagia, shortness of breath and even dyspnea occur; The latter is characterized by flushing, itching or rash on the skin around the application. If it is applied to the oral cavity, flushing ulcers or grayish white spots can be seen on the gums, tongue and oral mucosa. After wiping off the patch, local oozing wounds appear, and some even have swollen and thickened tongues.
The reasons for the above reaction are:
1. The concentration of purple liquid medicine is too high;
2. Too much dosage, such as too large application area and too many times;
3. The baby has delicate skin and poor adaptability to external stimuli;
4. Allergic constitution, allergic reaction.
Therefore, it is best for infants not to use or use less purple potion. If necessary, it should be noted that the concentration of purple liquid medicine should not be too high, which should be limited to 0.5%- 1%, and the application times should be 1-3 times, once a day. The scope of use is limited to the periphery of the lesion, and the use time is generally less than 3 days. In addition, people who are allergic and have had allergic reactions should not use it again.