After autologous bone tissue transplantation, the material is easy to survive without rejection. Most of them are taken from ilium, but also from ribs, tibia, skull and so on. Taking materials will cause the pain of beauty seekers and even complications. In the long run, bone absorption may occur, resulting in changes in appearance, which is difficult for patients to accept. It is unacceptable for subjects without special deformities. At present, it is rarely used in rhinoplasty and beauty. However, for the correction of complex nasal deformity or severe saddle nose, autologous bone transplantation is still needed. Beauty seekers from South Korea, Japan and the United States are more likely to accept autogenous costal cartilage rhinoplasty. Therefore, foreign countries often use autologous cartilage transplantation to beautify the nose. Ear cartilage and nasal septum cartilage have limited bone mass and are often used in combination with allogenic materials, which is called "cartilage cap prosthesis". The prosthesis wearing cartilage cap will not penetrate the tip of the nose, nor will it cause the tip of the nose to be red. Using ear cartilage and nasal septum cartilage alone to beautify the tip of the nose will also get good results. In recent years, more and more doctors in China have used autologous cartilage transplantation in rhinoplasty. Solid silica gel has good biocompatibility and low price, and is one of the first choice materials for clinical rhinoplasty. Its main disadvantage is that it can not establish blood circulation with the body, and it is only wrapped by fibrous tissue, so it can penetrate the skin at the weak part of the tissue. Due to the contracture of fibrous capsule, the "body surface bulge" of silicone prosthesis can appear, which affects the appearance effect. In recent years, doctors have added an ear cartilage cap to the top of the silicone prosthesis to reduce the probability of the prosthesis leaving the skin. In addition to the good biocompatibility of solid silica gel, the swelling body also has its microporous structure, and human tissues, cells and blood vessels can grow into micropores to form tissue connections, just like autologous tissues. The high cost of puffing affects its universal application. Allogeneic tissue Allogeneic bone and cartilage, after special treatment, play a temporary mechanical support role as rhinoplasty materials, and are finally replaced by autologous bone. Because of the difficulty in source, quantity and quality, allogeneic tissue is rarely used in China. Korea and Japan use it more. Hyaluronic acid Hyaluronic acid is one of the components of human dermal tissue. Using the expansion of hyaluronic acid, the sunken bridge of the nose is raised. However, hyaluronic acid will be slowly absorbed by the human body, so if you want to maintain the effect, you need to inject it on time, otherwise the effect will gradually fade and finally disappear completely. This method is limited to the slight depression of the bridge of the nose and has no ideal effect on the shaping of the nose tip. Before rhinoplasty with bioengineering materials, a little cartilage is taken from the patient, and a personalized nose is obtained through bioengineering technology, and then it is slightly trimmed for rhinoplasty, which can also be called organ reconstruction. Its advantages are no rejection, natural shape and strong repair function. Bioengineering material rhinoplasty is generally considered as the development direction of rhinoplasty in the future by the medical community.