At an earlier medical seminar, doctors appealed to customers not to use botulinum toxin injection as much as possible. This substance has very serious sequelae to the body and skin. It used to be very popular in Europe, but now dermatologists don't like to use it. After injection of botulinum toxin, the skin is only temporarily tightened and the effect lasts for 3-4 months. However, the sequelae are permanent. Because there are many nerve lines in the skin, the nerve lines are damaged after repeated injections, resulting in facial movements that cannot occur naturally. In the later stage, the skin will be severely relaxed. Long-term use will lead to cancer. The operation of fat filling is mainly to extract fat from oneself and sterilize it in the injected skin. However, strict disinfection measures must be taken. If it is not in place, inflammation will occur. Moreover, these substances are easily absorbed by the skin. Once absorbed, the skin needs to be refilled. This kind of injection is expensive and painful. The skin can't always expand and contract, which will lead to more relaxation of the skin. Moreover, the problem of skin aging is not only a local problem, but also a comprehensive problem of tension, lack of elasticity and cell absorption ability. Injection can only partially solve the problem. Therefore, if active products are used, cells will be activated and the problem will be further improved. Can achieve the effect of lasting security.