In A.D. 1934, Meyer, a professor of ophthalmology at Columbia University, isolated hyaluronic acid from bovine vitreous for the first time and analyzed its structure. Because it comes from

Glass-like extraction of uronic acid.

In the 1960s and 1980s, the price of hyaluronic acid used in ophthalmology was as high as $ 654.38+0 million per kilogram, so it was rarely used in the market.

1993, German doctors injected hyaluronic acid directly into the synovium of patients' bones and joints for the first time. The results show that patients can quickly eliminate joint pain and restore walking ability. Since then, it has also been used to treat arthritis in western countries. In terms of price, the price of hyaluronic acid in cosmetics is generally RMB 0/.5-20,000 per kilogram, RMB 0/10,000 for food grade and RMB 50,000-60,000 for pharmaceutical grade.