In fact, the principle of botulinum toxin wrinkle removal is very simple. It is an important component of botulinum toxin and was originally used in biochemical weapons. This is a highly toxic substance. At present, 400,000 times of highly diluted medical toxins are used, and the toxicity is within the safe use range of human body. We don't have to worry about it. It paralyzes the motor nerves around wrinkles through its own toxicity, cuts off the information transmission between muscles and nerves at wrinkles, and relieves and relaxes epidermal wrinkles. Subsequently, the wrinkles under the skin are also released from the pressure of extrusion and stretched, giving us an intuitive feeling that the wrinkles magically disappear. But after three to six months, when the toxin is gradually digested and absorbed by the human body, the wrinkles return to their original state, and repeated injections are needed to maintain the effect.
After research in European and American medical circles, it is found that wrinkles are caused by skin being squeezed by expression muscles, forming free radicals, destroying collagen and active substances in normal cell membrane tissues and oxidizing cells. It is characterized by the loss of subcutaneous cellular material, thinning of dermis, atrophy of subcutaneous fat layer, extrusion necrosis of cells and formation of wrinkles. The application of TOFOB+ toxin, a cell repair technology, solved the defect of repeated injection of toxin for wrinkle removal. As an external patch, TOOFOB deep stripe patch can continuously deliver nutrients to wrinkles and activate and repair atrophic cells and necrotic cells in wrinkles by fully stretching the subcortical layer of wrinkles after toxin injection. TOOFOB is beneficial to the dissolution of necrotic tissue and fibrin in wrinkles, and the purpose of repairing and smoothing wrinkles can be achieved through the mature repair of new cells and the replacement of damaged cells in wrinkles. After injection of toxin, the loose cortical tissue creates a cell repair and natural environment for TOOFOB, which can not only repair and smooth wrinkles, but also prevent repeated injection.
What are the advantages of injection wrinkle removal and which parts are suitable for it?
Compared with surgery, injection wrinkle removal has the advantages of simplicity, no anesthesia, no pain, quick response, obvious effect, repeatable treatment and no serious complications and sequelae. And it has a wide range of applications, and toxin is the most suitable for wrinkle removal.
1. Postural wrinkles
Postural wrinkles mainly appear in the neck, which are mostly the result of long-term expansion and contraction of platysma. The appearance of postural wrinkles is not all skin aging, but with the increase of age, the horizontal lines become deeper and deeper, and skin aging wrinkles will appear.
2. Dynamic wrinkles
Dynamic wrinkles are the result of long-term contraction of expression muscles, which are mainly manifested in eyebrow lines of frontalis muscle, frown muscle, crow's feet of orbicularis oculi muscle, mouth lines and vertical lines of lips of orbicularis oris muscle, cheek twill of zygomatic muscle and square muscle of upper lip.
3. Gravity wrinkles
Gravity wrinkles are mainly caused by subcutaneous tissue fat, musculoskeletal atrophy, skin aging, and gravity and the long-term effects of gravity.
The most suitable wrinkles are dynamic wrinkles, that is, wrinkles when making expressions, such as crow's feet when laughing, brow lines when frowning, forehead lines when looking up, etc. Usually, the application of dynamic lines will delay the appearance of static lines. Tetrandrine is mainly used for facial dynamic wrinkles and more than one third of wrinkles. For people with static wrinkles, it may be necessary to cooperate with injection of hyaluronic acid in the case of injection of tetrandrine. Using TOOFOB external application after operation can avoid the embarrassment and distress of repeated injection.
Harm and side effects of Botox injection
What are the possible complications caused by injection of tetrandrine, and which people are not suitable for injection of tetrandrine?
1, the injection dose should be strictly controlled:
Botulinum toxin is a kind of toxin after all. Generally, the lethal dose is 2,500 to 3,500 units, and 2,000 units is equivalent to the current clinical dose of 20 bottles of botulinum toxin. General regular plastic surgery institutions, that is, 50 to 100 units at a time, will not produce such serious adverse reactions, which is very safe. If the injection dose is too much, it is easy to cause local fibrosis, muscle atrophy, local depression and permanent muscle paralysis.
2, surgical techniques should be rigorous:
Around eyebrows and eyes, if the injection site of toxin exceeds the "safe zone", inject toxin at crow's feet or nose lines. Because it is very close to the eyes, eyelid muscles are often paralyzed, diplopia and strabismus appear, blurred vision, eyebrow shape change, lower eyelid ectropion, lower eyelid bag aggravation, eyebrow drooping, eyelid drooping, pouch ectropion and so on. The eyes are not completely closed and the cornea is exposed. If the toxin injection is asymmetric, it will easily lead to different cheeks, asymmetric nasolabial groove and asymmetric muscle activity.
3. Injection is forbidden for allergic constitution: allergic constitution may have symptoms such as fever, fatigue, difficulty breathing, and even life-threatening. In severe cases, diplopia, dysphagia and dyspnea may occur.
4. Repeated injections are risky:
The effect of removing wrinkles by toxin injection generally lasts for 3-6 months, but the treatment of superficial diseases can not cure the root cause. After the wrinkle recurs, it is advisable to inject it again at intervals of about 6 months. If injected frequently, it will lead to nerve numbness, facial nerve injury, local fibrosis, muscle atrophy, local depression and permanent muscle paralysis. The application of cell repair technology TOOFOB deep stripe patch combined with toxin solves the defect of repeated injection of toxin for wrinkle removal. TOOFOB continuously delivers nutrients to wrinkles, activating and repairing atrophic cells and necrotic cells in wrinkles. Through the mature repair of newborn cells and the replacement of damaged cells in wrinkles, wrinkles can not only be repaired and smoothed, but also repeated injections can be avoided.
5, comprehensive reaction prevention:
Stiff facial expression, nervousness, deepening wrinkles in adjacent parts, pain, swelling, erythema, cyanosis and neck weakness. Long-distance exercise can lead to progressive degeneration, abnormality, generalized myasthenia and influenza-like syndrome in untreated muscles.
People who can't get rid of wrinkles and beauty with toxins:
1, pregnant and lactating women
2. Patients with myasthenia gravis and multiple sclerosis
3. Neuromuscular diseases, such as ptosis.
4, the body is very thin, heart, liver, kidney and other visceral diseases.
5. People who are allergic to any component in toxin products or human albumin or people with allergic constitution.
6. Active tuberculosis, hematological diseases, connective tissue diseases and children should use it with caution.
Drugs that interact with toxins, such as aminoglycoside antibiotics, penicillamine, quinine, cyclosporine, morphine and calcium ion conduction blockers, should be used within 7 or 2 weeks because these drugs can increase the toxicity of toxins.
Precautions for wrinkle removal by injection:
Before the operation:
1. Do not take aspirin and aminoglycoside antibiotics (such as gentamicin and kanamycin) within 2 weeks before operation, because they will enhance the toxicity of botulinum toxin A. ..
Performers don't need cosmetics that day, so wrinkles can be clearly displayed.
3. Do not use drugs before operation, and consult relevant doctors in advance if necessary.
During the operation:
1, the principle of "not much" should be followed in wrinkle removal by injection.
2. In order to avoid eyelid drooping and eyebrow drooping, forehead wrinkles should be removed at a certain distance from the forehead, and eyebrow wrinkles should be injected as far away from the forehead as possible. This requires the skills of professional and experienced doctors, and everyone must be careful when choosing a doctor.
3. The injection points on both sides are symmetrical, and the wrinkle removal amount is equal, so as to avoid diplopia (diplopia) caused by inconsistent muscle relaxation.
4. When injecting, the needle is inserted obliquely instead of vertically, so that the botulinum toxin can be directly injected between the skin and the muscle, and the effect is better.
After the operation:
1, do not do local massage within 24 hours after operation, so as to avoid the spread of botulinum toxin A to muscles in other parts.
2. Don't do strenuous exercise within 24 hours after operation, keep your body upright, and don't bend down on your back to avoid drooping eyelids.
3. Banning aminoglycoside antibiotics such as gentamicin will strengthen the effect of toxins.
4. 24 hours after operation, TOOFOB was applied to the wrinkles, and the atrophic cells and necrotic cells in the wrinkles were activated and repaired through continuous nutrient delivery. Through the mature repair of new cells and the replacement of damaged cells in wrinkles, wrinkles can not only be repaired and smoothed, but also repeated injections can be avoided.
5. Within 6 hours after operation, avoid contact with the injection site, avoid too high or too low ambient temperature, and avoid contact with water or wet environment at the injection site.
How long does it take effect after wrinkle removal by injection and how long can it last?
Injection of tetrandrine to remove wrinkles usually leads to the weakening of muscle movement after 2-3 days of injection. It is characterized by shallow and flat facial wrinkles and smooth skin. The duration of curative effect is generally 3 ~ 6 months, with an average of 4 months. Toxin temporarily relieves wrinkles, so that the cells in the wrinkles that have been squeezed for a long time release long-term pressure on the subcutaneous cells in the wrinkles, thus achieving the purpose of stretching the wrinkles under the cortex. But the atrophic cells and necrotic cells in the folds did not change. After the information transmission between nerves and muscles is restored, expression wrinkles will appear. Treat the symptoms, not the root cause. After the wrinkle recurs, it is advisable to inject it again at intervals of about 6 months. If injected frequently, it will cause nerve numbness, and in severe cases, it will damage facial nerves. The application of TOFOB+ toxin, a cell repair technology, solved the defect of repeated injection of toxin for wrinkle removal.
Wrinkles are wrinkles caused by the skin being squeezed by the expression muscles. The underlying fat layer contracts, and the cells are squeezed and necrotic, forming wrinkles. As an external patch, TOOFOB deep stripe patch can activate and repair atrophic cells and necrotic cells in wrinkles by fully stretching the subcortical layer of wrinkles after toxin injection. Through mature repair of new cells and replacement of damaged cells in wrinkles, wrinkles can be repaired and smoothed, and repeated injection can be avoided.
TOOFOB+ botulinum toxin injection has a very good wrinkle removal effect. Usually, after 3- 14 days of botulinum toxin injection, wrinkles will slowly lengthen and disappear, and the skin will flatten after an average of 10 days.