You are talking about crooked mouth, that is, a nasolabial groove disappears and facial muscles are paralyzed, so the mouth is crooked. The cause is peripheral facial paralysis. The following is the introduction of peripheral facial paralysis. Peripheral facial paralysis, also known as Bell's palsy, is a common clinical disease caused by facial nucleus or facial nerve lesions. The most common diseases are facial neuritis, followed by tumors near the facial nerve canal (such as parotid tumors), inflammation (otitis media, mastoiditis and purulent lesions of temporal bone), trauma or tumors at the cerebellopontine angle and skull base (such as acoustic neuroma, meningioma and chordoma), or facial nerve injury caused by resection of these tumors. In addition, it can also be seen in skull base inflammation and temporal bone fracture. For Bell's palsy caused by facial neuritis, most scholars think it is related to facial nerve ischemia and virus infection, and some even think it is related to genetic factors. The main clinical manifestation is facial expression muscle paralysis, and the upper and lower muscles are often equally involved. Eyebrows droop on the affected side, forehead wrinkles disappear, and frowning and raising eyebrows can't be done. Due to the paralysis of orbicularis oculi muscle, the affected eye fissure is larger than the normal side, which can not be closed, and the lower eyelid is everted. Because the lacrimal sac mouth can't meet the conjunctiva, it hinders the drainage of tears, and the affected side often tears. The nasolabial groove of the affected side becomes shallow or disappears, the corners of the mouth droop, the corners of the mouth are often pulled to the healthy side, grinning or laughing is obvious, and it is impossible to drum the cheeks and whistle. The mouth of the affected side drools, and food tends to stay between the alveoli and cheeks. When the facial nerve is involved before the chorda tympani nerve branches, or the chorda tympani nerve is involved at the same time, in addition to the above symptoms, there may be taste disorder in the first two thirds of the tongue, and saliva on the affected side is reduced. If the lesion is located above the facial nerve canal, the nerve fibers innervating the stapedius muscle are also involved, which may be accompanied by auditory hypersensitivity of the affected side. When the lesion is located in the geniculate ganglion, there will be pain in and behind the ear, hypoalgesia in the auricle area, and blisters in the auricle or tympanic membrane. According to the obvious clinical manifestations, the diagnosis is generally not difficult, but it needs to be differentiated from peripheral facial paralysis caused by pontine disease. The latter is often accompanied by other cerebral palsy and cerebellar signs, as well as contralateral pyramidal tract signs. Treatment shows that complete facial paralysis not only affects the face, but also causes conjunctivitis, corneal exposure injury, inflammation and ulcer, and even blindness, which should be treated actively. (1) Medical treatment 1. Drug therapy is suitable for the adjuvant treatment of facial neuritis, peripheral facial paralysis caused by partial facial nerve injury and facial nerve anastomosis. Commonly used drugs are: prednisone 10mg, taken orally, three times a day, with 15 days as a course of treatment. It is suitable for acute facial neuritis. Galanthamine 2.5 ~ 5 mg, 1 time/day, intramuscular injection. 15 days is a course of treatment. Vitamin B 1 100mg, once a day, intramuscular injection, 1 5 days as a course of treatment, and can be used repeatedly after a few days' rest. Vitamin B 12 1mg, daily 1 time, intramuscular injection, the course of treatment is the same as vitamin B 1. Nicotinic acid 100mg, taken orally three times a day, can be used continuously for 1 ~ 2 months. Other vasodilators can also be used. Danshen tablets, 4 tablets each time, 4 times a day, taken orally. Or 500ml of low molecular dextran and 24g of Danshen injection, once a day, 1 0 ~15 days as a course of treatment. 2. Physical therapy such as infrared ray, induction electricity, iodine penetration and short wave can also be combined with the above drug treatment. Electrical stimulation can be used in the second week of the course. If facial muscle contracture has occurred, electrical stimulation should not be used. Massage and acupuncture also have certain curative effects. (2) The facial nerve rupture caused by injury should be treated by surgery as soon as possible. Facial paralysis caused by facial neuritis has not improved after 4 months of treatment and follow-up. When it is diagnosed as degeneration by electric diagnosis, surgery should be performed. The facial nerve was preserved during CP angle operation, but facial paralysis did not improve after 6 months of follow-up, and there was no electrical activity in facial nerve conduction velocity and electromyography, so surgery was needed. 1. Plastic surgery is to correct facial asymmetry through surgery. It is suitable for patients with facial paralysis, positive facial nerve degeneration test and irreparable facial nerve. Metal wires, nylon wires or fascia strips are often used to pull the corners of the mouth or eyes, or to cut off the muscles of the healthy cheekbones to make the muscles on both sides of the face symmetrical in strength or appearance. 2. Different surgical methods are selected for facial nerve repair according to the etiology, such as facial nerve incision or intraoperative trauma. If possible, neurorrhaphy should be performed when injured. Patients with facial nerve compression were treated by craniotomy and facial nerve decompression. For those who cannot do facial nerve anastomosis directly, the peripheral segment of facial nerve can be anastomosed with the central segment of other cranial nerves. There is facial-accessory nerve or facial-hypoglossal nerve anastomosis. The disadvantage of facial-sublingual nerve anastomosis is that one side of the tongue is muscle atrophy after operation, so it is not suitable for people whose main occupation is pronunciation, such as teachers and broadcasters.