The most helpless thing I have ever seen is that she and it met, hated and killed each other in their best years, but they were still inseparable and never left.
He and she are in love
It is: Chloasma
As far as spots are concerned, it is really easier to get spots on the Tibetan Plateau. It is also more difficult to remove freckles. Why?
Take Lhasa as an example. Lhasa is known as the "City of Sunshine", with an annual sunshine time of 3,005 hours. Sunlight is one of the main culprits of spots. Causes of chloasma:
Gene related
Epidemiological studies show that chloasma mostly occurs in people with Fitzpatrick III/IV skin, which means we Asians Women are most susceptible to chloasma.
Sex hormone levels are related
Chloasma mostly occurs in women, and immune experiments show that the disease is clearly related to estrogen and progesterone levels. Oral contraceptives and pregnancy may aggravate chloasma.
Related to ultraviolet irradiation
Ultraviolet rays can induce keratinocytes to secrete paracrine factors such as fibroblast growth factor, endothelin-1, opioid-melanocyte-stimulating cortinogen, etc. In addition, ultraviolet irradiation can also cause keratinocytes to produce NO and the inflammation regulator histamine, which can induce an increase in local melanin synthesis.
Related to skin barrier dysfunction
In chloasma lesions, basement membrane zone cells appear vacuolated, the expression of type IV and VI collagen is significantly reduced, and free melanin is released in the superficial dermis. and increased melanophages, which are highly suggestive of skin barrier dysfunction.
Related to inflammation
Inflammation in chloasma lesions is not manifested by an increase in inflammatory cells such as white blood cells or lymphocytes, but by the expression of vascular endothelial growth factor in the epidermal basement membrane of the lesions. The latter can induce an increase in the number, size and density of blood vessels.
What are the symptoms of plateau chloasma?
Low oxygen content: Reduces skin resistance and repair ability, accelerates skin aging and the generation of spots.
Strong ultraviolet rays: can induce pigment rebound after chloasma treatment and destroy postoperative skin barrier function repair.
Dry air: Increases the difficulty of moisturizing after chloasma treatment.
Of course, we often say that there are no spots that cannot be removed, only the right method is not found.
Misconceptions about freckle removal:
Search for freckle removal in Moments, Weibo, and Zhihu, and many amazing products praised by the copywriters will pop up, including facial masks, ointments, skin care products, etc. If you use these products for a long time, your facial skin will experience itching, burning, dryness, and scaling. Stop immediately. Almost all of these products contain glucocorticoids that are prohibited in beauty products. You may become hormone dependent. Dermatitis, commonly known as hormone face.
Treating hormone-containing face is a long process. You should stop using hormone-containing ointments or masks under the guidance of a doctor, and do a good job of facial cleansing, sun protection and treatment. No freckle removal can be achieved overnight. Everyone loves beauty. When you love beauty, you should be vigilant and guard against falling into the sales trap of inferior cosmetics.