1. allergic constitution, intradermal allergy test (25μg/ml solution, intradermal injection of 0. 1ml) should be done before injection or after termination of treatment, and those with positive reaction are prohibited. 2. After the product is dissolved, it is forbidden to use if there are abnormal changes such as turbidity or flocculent precipitation. 3. When the characteristics of drugs change, it is forbidden to use them.