Desflurane, this product is suitable for anesthesia induction and maintenance during adult hospitalization or outpatient surgery; It can only be used as maintenance anesthesia for infants, not as induction anesthesia. Molecular formula: C3H2F6O.

For adults who have used some opioid analgesics before anesthesia, the initial dose of this product is 3%. Every 2 ~ 3 breaths, the dosage of this product increases by 0.5 ~ 1.0%. At the end of anesthesia, the concentration of this product is 4 ~ 1 1%, which can be combined with nitrous oxide or not to produce anesthesia for 2 ~ 4 minutes.

When this product is used as the main induction anesthetic, the incidence of upper respiratory tract irritation is high. After intravenous injection of thiopental sodium or propofol in adults, the initial dose of this product can be 0.5 ~ 1 MAC, and this product must be mixed with oxygen or nitrous oxide/oxygen.

counteraction

When this product is used to induce anesthesia, it may cause adverse reactions. Cough (34%), asphyxia (35%), dyspnea (30%), increased secretion, laryngeal spasm and pharyngitis occurred in 370 cases of adult anesthesia. 152 children had cough (72%), dyspnea (68%), laryngospasm (50%), increased secretion (2 1%) and bronchospasm.

When using this product to maintain anesthesia, the adverse reactions of 687 adults and children included headache, bradycardia, hypertension, sinus arrhythmia, tachycardia, nausea (27%), vomiting (16%), increased salivation, asphyxia, dyspnea, increased cough, laryngeal spasm and conjunctivitis.