The best majors of Shanghai Jiao Tong University School of Medicine: clinical medicine, stomatology, medical laboratory testing, and nursing are national-level specialty majors.

Shanghai Jiao Tong University School of Medicine was established by the Ministry of Education of the People's Republic of China, the Ministry of Health of the People's Republic of China and the Shanghai Municipal People's Government. , ranked among the "211 Project" and "985 Project", was selected into the first batch of China's "Excellent Doctor Education and Training Program", and is the subject leader unit of the National Clinical Skills Experimental Demonstration Center.

Shanghai Jiao Tong University School of Medicine was formerly known as Shanghai Second Medical College, which was formed by the merger of St. John’s University School of Medicine, Aurora University School of Medicine, and Tongde Medical School in 1952 during the national adjustment of colleges and universities. ; In 1985, it was renamed Shanghai Second Medical University. In 1997, the school approved the “211 Project”. On July 18, 2005, Shanghai Jiao Tong University merged with Shanghai Second Medical University to establish the Shanghai Jiao Tong University School of Medicine, which was established by the Ministry of Education and the Shanghai Municipal People's Government and entered the ranks of "985" universities. In November 2010, the college became one of the first batch of ten key universities jointly established by the Ministry of Health and the Ministry of Education.