Hello, according to your description, the skin has become slack and inelastic, and wrinkles have increased, mainly due to the discomfort caused by endocrine disorders. According to what you said, your condition is a normal physiological phenomenon. If you want to make your skin firm, you should pay attention to the details of your life, eat more foods rich in collagen, do more exercise to promote gastrointestinal motility, keep your stool smooth and avoid staying up late. Stick to it for a while and see if it works.