If you want to punch in 450, first of all, you should make jewelry every day and exchange the coins you need from Dalaran jeweler for drawings. Because after 450, the drawings of purple gemstones and the drawings of special prizes of jewelry itself will be exchanged with the coins of Dalaran jewelers. Of course, there are still some drawings that can be bought from local prestige. In winter, I will exchange debris and battlefield honor for drawings.
If you have a personal recommendation from an alchemist friend, please ask him to help you convert the colorful skills to 450, and then you can cut them.
I hope it helps you.