However, in the next four years, Qin Xiao's "period" seemed to disappear and never came again. Parents only want to send their children to the hospital. The doctor found that Qin Xiao didn't come except for her "period" and her breasts didn't develop. What's more, her voice began to be hoarse and her Adam's apple was raised, and a male-like reproductive organ actually grew on her original female reproductive organ.
The local hospital collected her relevant samples and sent them to Shanghai for testing. Finally, she was diagnosed as "congenital adrenal hyperplasia", which would make her body secrete a lot of androgen and appear "female pseudohermaphroditism" symptoms.
The cause of this rare disease is either consanguineous marriage of parents or genetic mutation. Qin Xiao's parents happened to be close relatives, and the reason was discovered.
Finally, on the basis of confirming that Qin Xiao has a uterus and an ovary with a chromosome of 46XX, the local hospital helped her to have plastic surgery for reproductive organs. And let her take exogenous glucocorticoid instead, to inhibit the aggravation of the disease, and also help her maintain the secondary sexual characteristics of women.
Extended data
The harm of consanguineous marriage
Inkin marriage, both husband and wife have too many similar genetic factors, and the offspring can't mutate from them, and the harmful genes are passed on to the offspring.
If this gene is autosomal recessive, its children may get sick because they are homozygotes of the mutation. So inbreeding will increase the risk of some autosomal recessive genetic diseases. Inbreeding increases the probability that children will get such a pair of homozygous or identical genes, and this correlation coefficient is called consanguineous coefficient.
China News Network-Parents close relatives get married, and daughters grow male reproductive organs in flower season.
Baidu encyclopedia-consanguineous marriage