Almost everyone knows the harm of smoking, but not everyone knows that smoking affects the effect of plastic surgery. Smoking after operation will affect the effect of cosmetic surgery, mainly because nicotine in cigarettes is at work. Nicotine affects wound healing and leaves scars. Nicotine can cause vasoconstriction and reduce blood flow in all parts of the body, and the skin is the first to be affected. When the blood flowing through the skin decreases, the oxygen obtained by the skin will also decrease accordingly. Without the support of oxygen, the wound will heal slowly, or even the wound will not heal. Even if the wound heals, due to lack of oxygen, once the stitches are removed, the wound with poor healing may split. The split incision is generally difficult to heal again, and even a wide scar will be produced after healing. In addition, nicotine can destroy people's immune function, reduce people's anti-infection ability and cause wound infection. Therefore, serious smokers are not suitable for plastic surgery, and those who are not too serious must definitely quit smoking within half a month before surgery and do not smoke within half a month after surgery. Nicotine is an odorous, bitter, colorless and transparent oily liquid with strong volatility. It can be easily oxidized to dark gray in air, quickly dissolved in water and alcohol, and easily absorbed by human body through nasal cavity, oral cavity and bronchial mucosa. Nicotine stuck to the skin surface can also be absorbed and penetrated into the body. Nicotine will have many effects after entering the human body, such as contraction of peripheral blood vessels in limbs, rapid heartbeat, elevated blood pressure, accelerated breathing, mental state changes (such as emotional stability or mental excitement), and promote platelet aggregation. It is the main accomplice of cardiovascular diseases such as cardiovascular obstruction, hypertension and stroke.