Methoxyethyl nitrate is the most commonly studied topical drug for the treatment of rosacea. At present, there are ointments, gels and lotions to choose from.

Nitrhydroxyethyl oxazole is an isopyrazole with antibacterial effect. The exact mechanism of the drug to improve rosacea symptoms is not clear, which may be related to its anti-inflammatory and immunosuppressive functions. It is also effective in treating papules and pustules, and can reduce skin inflammation and erythema. However, it usually has no effect on telangiectasia. The use of metronidazole is easily accepted by patients because it is convenient to use and has mild side effects. Only more than 2% patients have tingling, dryness, itching and burning sensation after use.

sulfacetamide sodium

Sodium sulfacetamide is also used for local treatment of rosacea. However, patients who are allergic to sulfonamides should avoid using such drugs. At present, there are several different types of sulfacetamide sodium lotions.

Clindamycin (clindamycin, clindamycin)

Although the local clindamycin preparation has not been approved by the Food and Drug Administration for the treatment of rosacea, its hydrogel and lotion can effectively treat rosacea and are easily tolerated by patients.

Aza acid

The well-known azalea acid used for treating acne vulgaris (commonly known as "acne", "acne" and "rosacea") can also be used for treating rosacea. In a randomized comparative study of patients with papular pustular rosacea, scientists compared the efficacy of 20% Rhododendron topical ointment and 0.75% nitrohydroxyethyl azole ointment. After 15 weeks of treatment, the two drugs have achieved the same curative effect, and both of them have obviously reduced the papules and pustules on the face of patients.

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