What causes the nose to be empty? Most of the causes of empty nose are that patients with rhinitis or nasal congestion excessively remove the inferior turbinate during nasal surgery after the failure of nasal laser, which destroys the structure of nasal cavity and nasal mucosa, makes the nasal cavity space of patients larger, and the airflow in the nasal cavity becomes a rotating vortex, and the nasal mucosa cannot feel the airflow, which makes patients feel the problem of nasal congestion. In addition, the nasal mucosa has been exposed to unfiltered air, which makes the ciliated cells in the nose begin to shrink excessively and deteriorate and be damaged by drying.
Why do people with nasal congestion feel that life is worse than death?
The nose is a precise organ, and the five senses can see the external nose, but breathing depends on the turbinate in the nasal cavity and the nasal mucosa above; Among them, the turbinate has the functions of detection, perception, transmission and adjustment. However, after the turbinate is defective, the brain can't receive signals, and the alveoli in the lungs can't form negative pressure with the turbinate, which makes it easy to feel breathless. If the turbinate is seriously injured, pulmonary fibrosis, pneumoconiosis, organ failure such as heart and brain, or loss of immunity may occur, making the patient's life worse than death, resulting in self-injury or injury or mental illness.
For example, on 20 13, 10125, a medical case was killed, which shocked Chinese mainland. The patient Lian Enqing took a dagger to the otolaryngology clinic of Wenling First People's Hospital to kill the chief physician Wang Yunjie; He was completely normal before the 20 12 nasal septum operation, but after the operation, he often said, "My nose is blocked and I feel uncomfortable", "I have a headache" and "I can't sleep all night", but it is no problem to go to other hospitals for examination. Finally, his family forced him into a mental hospital, which led to misfortune. In recent years, some patients in the United States, Canada and Chinese mainland can't stand the pain of runny nose.
Repair the lack of turbinate and save the patients with empty nose who are worse than death. In the medical treatment of empty nose, the operation is divided into two ways: traditional nostril suture and endoscopic minimally invasive surgery of sinus. The traditional method is to sew the nostrils, but it will cause inconvenience in appearance and life; However, in endoscopic sinus surgery, the materials used in the past can be synthetic, which may cause autoimmune rejection and discomfort.
In order to repair the lack of turbinate, some patients visited Dr. Anthony attalla, the world's top regenerative medicine scientist, in the stem cell regeneration laboratory of Wake Forest University. Dr Anthony attalla has developed artificial bladder, kidney and uterus, and transplanted them into living people for clinical experiments, among which animal experiments of skin regeneration are very mature.
Dr Anthony attalla said that if we want to use the concept of regenerative medicine to repair the patient's excessively excised inferior turbinate, we must use stem cell technology of regenerative medicine to make the patient's turbinate and nasal mucosa.
Among them, the material of turbinate is similar to cartilage tissue, and cartilage regeneration has been successfully realized by using the synthetic biodegradable scaffold of mouse subcutaneously transplanted chondrocytes. Therefore, if the patient's residual turbinate tissue is extracted and cultured, and then a synthetic biodegradable scaffold is placed at the nasal tissue, autologous cartilage regeneration may also successfully help the patient regenerate the turbinate, restore normal breathing, and get rid of the state of life is worse than death.