The first death case of monkeypox occurred in Los Angeles County, USA, which is the second known case of monkeypox in the United States. The first local death case of monkeypox was a patient hospitalized due to severe immunodeficiency. The local health department and the Centers for Disease Control and Prevention confirmed that the victims in Los Angeles County died of monkeypox. Patient's? The immune system is impaired. Once the virus enters the human body, it will propagate uncontrollably and spread to multiple organ systems. This is the second known death case of monkeypox in the United States, after the first death case of a patient with severely damaged immune system in Texas.

Authorities are still investigating victims in Texas to determine the role of monkeypox in the death. Monkeypox usually affects infants, pregnant women or people with weak immune system, but death is extremely rare. In the current epidemic of monkeypox, there have been nearly 58,000 cases and 65,438+08 deaths worldwide, not including the deaths in the United States. Rash can appear all over the body, 95% of cases appear on the face, 75% of cases appear on the palms and soles of the feet, and almost all parts of the body at the same time. About 10 day, the rash developed from maculopapular rash to blisters, pustules and finally scabs. After 3 weeks, the scab fell off and disappeared.

Systemic lesions range from several to thousands, with 70% cases affecting oral mucosa, 30% cases affecting cheeks and 20% cases affecting eyelids and cornea. Some patients may have severe lymphadenopathy before the rash appears, which is helpful for the differential diagnosis of monkeypox, because smallpox and chickenpox do not have lymphadenopathy. Monkeypox symptoms usually last 14 to 2 10 days. The mortality of this disease varies greatly, generally less than 10% of the confirmed cases. Most of the dead were children. The most important risk factor of monkeypox virus infection is close contact with other patients. In the absence of specific treatments and vaccines, the only way to reduce human infection is to raise awareness of risk factors and educate people about possible measures to reduce virus exposure.