Very effective. I have used both nano essence and nano essence. The difference is that the essence can be absorbed by itself without massage, while the nano essence needs massage by itself. I think the effect is much better than the essence. Of course, this is just my own feeling. For me, the masseter muscle and the root of rhinoplasty are the most obvious, the chin augmentation is more obvious, and the double eyelids are not so obvious. Maybe my double eyelids are also related. I used it myself and thought it was good before I started acting as an agent. But there are many fakes on the market now, so you need to polish your eyes! The cost is relatively high, and the cheap one must be fake.