At the beginning of the disease, fever, crying and refusal to eat were the main manifestations. The local skin is red, hard, slightly swollen, and the boundary is unclear. The red skin turns white after being pressed. Within a few hours to a day, the lesion can expand rapidly, the skin becomes soft, the color of the central part turns dark red, the skin is separated from the subcutaneous tissue, and the skin feels floating when palpated. There will also be "fluctuations" when pus accumulates too much. In the late stage, subcutaneous tissue and skin were necrotic and exfoliated in a large area. Severe cases may be complicated with bronchopneumonia, lung abscess, septicemia, high fever, dyspnea, bleeding tendency and even coma.

Attention should be paid to distinguish it from diaper rash and scleroderma. Diaper rash skin is red but not swollen, scleroderma skin is swollen but not red. Both of them have no systemic symptoms of infection. Early local reddish, no "floating feeling" when touching, can use broad-spectrum antibiotics, strengthen skin care, close observation. Once the skin turns dark red and feels "floating", multiple incisions should be made as soon as possible (usually about 5~7), which can often control the further development of the lesion. Each incision is about 1cm long, and it is forbidden to make only one large incision, so as to avoid skin rupture and difficult to heal. If necrosis occurs, the necrotic skin should be removed at any time. Change dressing after operation to keep smooth drainage; Skin grafting should be done as soon as possible after the wound is cleaned. Antibiotics should be combined as soon as possible, and antibiotics such as penicillin are generally used. In addition, systemic support therapy should be strengthened to improve the resistance of sick children and promote wound healing.