What are the factors that affect the success of IVF?
1. The woman's age is the main factor for the success of IVF.
Because the quality of eggs will gradually age with age, the success rate of IVF aged 25-35 is the highest.
The success rate and live birth rate of & gt40-year-old IVF are greatly reduced.
2. The influence of various infertility factors
The woman's severe endometriosis and polycystic ovary will affect the success of IVF.
The success rate of IVF will also be affected by the serious sperm shortage or excessive abnormal sperm.
3. The situation of women's uterus
Whether the endometrium is healthy or not is the most important factor affecting embryo implantation.
Endometrial injury, adenomyosis, endometritis, endometrial lymphadenopathy or other endometrial lesions may affect embryo implantation. The endometrium is too thin and too thick to be transplanted!
Before IVF, it is necessary to check the uterus and adjust the uterine environment.
4. It's 4. DNA chromosome abnormality?
Even if the embryo culture is successful, the failure rate and abortion rate of patients with abnormal DNA chromosomes are high.
5. Have you cultivated excellent embryos?
Excellent embryos are the main prerequisite for the success of IVF. Six-level classification method of embryos: new embryos I-IV can be transplanted in vitro, and I and II are excellent embryos.
6. Strengthen exercise and enhance physical fitness.
It is not only beneficial to improve the quality of sperm eggs, but also beneficial to the survival rate of excellent embryos and improve the success rate of test tubes!
7. Mentality is very important!
Keep a positive and optimistic attitude. I believe the baby will come. Don't worry too much. Bad emotions have a great influence on the successful implantation and development of embryos!
Whether or when IVF will succeed is uncertain. This is related to many factors, such as the mother's own physique, age, etiology and so on. And the differences in medical technology. So it is possible that the successful prices of IVF for two different mothers are quite different.
Generally, it takes about 15 thousand for a IVF to succeed. If the condition is complicated, it may cost tens of thousands to be an IVF three or four times.
Being a test-tube baby is sometimes like winning the lottery. Some people fail seven or eight times, while others succeed once. Of course, in the process of making test tubes, doctors will definitely choose the best quality embryos for implantation.
As for the mother's poor physical condition before the test tube, the doctor will also adjust the mother's body to the best pregnancy state. At the same time, some advantages and disadvantages in the conditioning process will also be clearly explained by doctors. Relaxing your mind and being too nervous will also affect the implantation of embryos on the endometrium.
After finishing the test tube, you should lie down and rest for a while. The length of time varies from person to person. Some women have to lie down for more than half a month after finishing the test tube, while others only need to lie down for two or three days. Try not to do manual labor at ordinary times, and keeping a comfortable mood is the best state.
Apart from accidents, the most important factors for the success of IVF are of course the mother's own physical condition and the husband's sperm condition.
Let's start with the man's semen. If the husband is older, has a bad habit of smoking and drinking, is obese and does not like sports, and the sperm activity rate is poor, even if he chooses better sperm, the quality of the fertilized egg may still be poor and he cannot survive in the female body.
Besides, the woman's situation is complicated.
1. Endometrial status
If intrauterine adhesion occurs after induced abortion or other reasons, it will damage the endometrium;
If there is endometrial hypoplasia, it means that the endometrium is thin;
Both of the above may lead to poor endometrial receptivity, failure of fertilized eggs to grow in the endometrium and failure of test tubes.
Therefore, once endometrial lesions are found, IVF should be performed after gynecological clinical treatment is improved, which can improve the success rate.
2. Uterine body condition
If there are adenomyosis, hysteromyoma and adenomyoma;
If there are congenital uterine dysplasia such as mediastinal uterus, unicornuate uterus and bicornuate uterus.
Both of the above factors may lead to abnormal uterine anatomy and affect the further growth of fertilized eggs.
Therefore, once serious adenomyosis and other diseases are found, IVF technology should be carried out after drug or surgical treatment is perfected. If. There is congenital uterine dysplasia in mediastinal uterus, and it is feasible to transplant the uterus after repair and plastic surgery if necessary.
3. Endocrine status
If women have abnormal female hormones such as luteal insufficiency and hyperprolactinemia, it is easy to increase the risk of miscarriage after pregnancy.
If there are metabolic diseases such as insulin resistance and diabetes, the risk of miscarriage will also increase.
Therefore, if hyperprolactinemia is found before pregnancy, the test tube should be carried out after the drug conditioning is normal; If there is metabolic syndrome, it should be improved before conception.
4. Psychological factors
The process of pregnancy is very complicated, and psychological factors also have an important influence. Infertile women bear greater social pressure than men. Haste makes waste, and anxiety is not conducive to pregnancy. Know how to relieve stress and adjust mood appropriately.
It's not easy to get pregnant, and I cherish it. I hope mommy who wants to be a test tube can have healthy children. If you have a basic disease, please be sure to go to the corresponding department for treatment and improvement before IVF, not just for quick.
Hello, I'm glad to have the opportunity to answer your questions. I hope our answers will be helpful to you.
First of all, there are many factors that will affect IVF. The specific factors will vary from person to person. Some people may succeed once, while others may go through a long process. Of course, the specific influencing factors can be summarized as follows:
First, the age of women.
Generally speaking, the older you get, the lower the probability of fertilization, especially when you are 25 -35 years old. However, if you are over 35 years old, ovarian function and egg quality will also decrease significantly. At this time, the success probability of IVF will drop significantly.
Second, the difference of ovarian reserve function.
Ovarian reserve function refers to the number of primordial follicles contained in ovarian cortex, which represents the ability of female egg quality and quantity, so this is also very important.
Third, infertility, differences in etiology.
It depends on the reason why you are infertile, such as oligospermia, azoospermia or a large number of abnormal sperm, so the success rate is relatively low, but if there is not much difference, just being old or something else, then it is easier to succeed.
Third, immune factors.
It is strange that the abnormal increase of natural killer cell activity in whole body or local area may have toxic effect on embryos and is not conducive to planting, so the success rate is relatively low. The better the immunity at ordinary times, the more you suffer.
Fourth, the spiritual aspect.
Being good at decompression, or having a relaxed psychological pressure, IVF is often more likely to succeed, but it is more difficult if you are anxious or often stay up late to work overtime.
"Why did my IVF fail many times? Others can succeed once. ""Why didn't I respond to the ovulation needle? " "What is the reason? Everyone else can succeed, I can't "and so on. At present, IVF is a very important way to treat infertility, and there are also many demanders. Although the success rate is gradually improving every year, some people still fail many times, and some people succeed once. Why? What caused the test tube to fail?
Causes of pipeline failure:
1, no response to ovulation-stimulating drugs, or poor response, so that the ovary can not produce enough mature eggs.
2. Due to the special reasons of pelvic anatomy, it is difficult or even impossible to take eggs.
3.20% of the eggs cannot be fertilized due to their own reasons or too few or too weak sperm.
4.20% fertilized eggs can't develop or degenerate normally and can't be replanted into uterine cavity.
5. Although embryos can be implanted into uterine cavity, 80% of them cannot be implanted or become pregnant.
In addition, with the increase of women's age, the number and quality of eggs will begin to decline, especially after the age of 35. The pregnancy rate of 40-year-old women will drop below 10%, the possible pregnancy rate of 45-year-old women will be below 5%, and the best childbearing age is between 23 and 35 years old. The decrease in the number and overall quality of eggs is one of the main reasons for the failure of test tubes.
In addition, the fertilized egg failed. After the egg is taken out, it should be combined with male sperm to form a fertilized egg. The failure of this link is related to the quality of eggs and sperm, and it is not easy to predict in advance.
Generally, couples who fail in this link can't find the specific reasons for infertility after many years and projects. This shows that the reason why they can't get pregnant is probably because of the poor quality of eggs or sperm. The proportion of this situation is about 3%. The quality of eggs has a great influence on this link, but sperm also has a certain role.
Whether an embryo can be formed depends on the quality of the fertilized egg. If the fertilized egg is not good, or the quality of the embryo formed is not good, it will lead to failure and the transplantation cannot be carried out.
When the transplantable embryo is transferred to the mother, the failure rate of this link is relatively high, which is more obvious than that of older women, especially those after 40 years old.
There are no secrets, just gambling. Gambling on luck will block the probability. You lose, you lose! Many people I know are successful in transplanting one follicle and one embryo at a time, and the probability of each person is incalculable.
My best friend Dabao Bao Xiao is a successful person. Talking about feelings 1, the hospital should choose the right one. There is a difference between one-year 10000 patients and one-year 1000 patients. Moreover, the technology and vision of large hospitals have kept up with the world level.
2. Choose the right doctor. Choosing the right doctor is the right plan. Can get the right eggs. Young doctors, chief physicians and deputy chief physicians in good hospitals are the first choice.
3, the mentality should be right. This requires the attitude of holding a dead horse as a living horse doctor, and the success rate is high.
The ancients said. There are three kinds of unfilial, and the last one is the biggest. Although people's ideas are very different from those of the ancients now. There are many people who belong to the Dinh family. But for various reasons, many people who want to have children can't get pregnant. With the development of social science and technology, IVF is also a method.
IVF is divided into several processes: ovulation induction therapy. Egg retrieval, in vitro fertilization, embryo transfer, corpus luteum support, pregnancy decision.
In these processes. Among them, ovulation induction therapy is the most critical. Because not every egg can be fertilized. Not every fertilized egg can develop into a viable embryo. Therefore, it is necessary to take multiple eggs from the mother to ensure the smooth transfer of embryos.
Pay more attention to nutrition after IVF transplantation. Drink more water. On the first day after one month, it was mainly liquid food. There are many staple foods, mainly digestible foods. Don't eat spicy and cold food, eat more fruits. Ensure nutrition supply.
After in vitro fertilization and embryo transfer. Expectant mothers don't have to worry too much. Keep a normal heart and a happy mood. For the development of children. It is also a good support.
Under normal circumstances, the monthly natural pregnancy probability of normal couples of childbearing age does not exceed 20%. In other words, not every couple can have a baby every month. Similarly, IVF is not successful every cycle. At present, the success rate of mature and standardized reproductive centers in China is generally around 50%, but this is only big data in the big environment and does not represent the success rate of individuals. Specifically, it has a lot to do with the age of an individual, the function of the uterus and ovary of the body, etc. Everyone is different. Some people are older, but their physical conditions may be successful for a while; Moreover, some people are old, but they have physical problems of one kind or another, and it may take two or three times to succeed, so it is generally impossible to say so. The specific situation requires the doctor to look at your inspection report and make targeted analysis and suggestions for you according to your actual situation!
With the increasing social pressure, there are more and more infertile people. Many people have suffered a lot in order to have a baby of their own. Of course, IVF also gives them one more choice. Although IVF is mature now, there is no guarantee that 100% will be successful.
So what factors affect the success rate of IVF?
1, age
The woman's age is the key factor affecting the success of IVF. The success rate is the highest when the woman is 25-35 years old. If she is over 35, her success rate will drop greatly. The older she gets, the lower her success rate will be.
2. Endometrial environment
The uterus is where the baby will stay for ten months. If the endometrium is damaged or there are uterine diseases, it may lead to the failure of embryo implantation and affect the success rate. In vitro, the demand for endometrium is also very high, even if it is too thick or too thin, it will make it difficult for embryos to implant. Therefore, many people will ask patients to have hysteroscopy before transplantation.
3. Embryo quality
Although the embryo quality also means that the younger the quality, the better, but there are also many young people with poor embryo quality, and when the embryo is not good, it will not be fertilized, so high-quality embryos are an important condition for success.
4. Chromosomes
Some couples have chromosomal abnormalities. Although these can be conceived in vitro, the failure rate and abortion rate are high.
5. Mental state
Psychological state is crucial to the success rate of test tube. Many people are inevitably nervous in the test tube, whether psychologically or economically, but if they are too nervous, they are prone to endocrine disorders and it is difficult for embryos to implant. Test tubes are a long way. Since you choose to leave, you should keep an optimistic attitude, so as to improve the success rate.
I wish all the sisters who choose test tubes and prepare test tubes success!