As a tool for tissue regeneration, stem cell exosomes have emerged. Their advantages are: overcoming the limitations and risks of traditional stem cell therapy, setting obvious targets, opening up a new perspective for tissue repair and regeneration, and setting off a frenzy of beauty and anti-aging. Exosomes are vesicles with double lipid structure, with a diameter of 40 ~ 100 nm and a density of1.10 ~1.18g/ml. At first, they were considered as by-products of cell metabolism, but recent studies have found that foreign bodies play a role in cell communication and are the medium of cell secretion. Exosomes can transfer DNA, RNA or protein between cells, thus affecting the function of recipient cells. The application mechanism of foreign bodies in cosmetology is 1. Exosomes that regenerate fresh stem cells can migrate to damaged areas, activate skin stem cells and promote skin cell regeneration. 2. Repair damaged cells and repair damaged skin cells in all layers. Regenerating healthy cells can repair damaged skin cells in all layers. Stem cell exosome complex factor can be stored in skin tissue for a long time, and it plays a role by regulating human skin microenvironment, which belongs to physiological repair and is safer and more effective.