1, can a change of blood really keep you young forever?
Everyone has a young dream, especially a woman who wants to be young forever. Recently, some media reported that an American company began to try an anti-aging method: replacing the blood of subjects with the blood of young people, with the intention of helping them "return to youth". As soon as the news came out, many beauty lovers began to stir. At the same time, some people question whether this way of "rejuvenation" is reliable. Are there any potential health risks?
The blood of young mice can rejuvenate mice. Can "changing blood" really resist aging?
Previously, the American company "Ambrosia" had recruited 600 volunteers to receive1blood donated by blood donors aged 6 to 25 within two days. Participants need to pay $8,000 for this.
Within a month, 30 participants received about two liters of blood cell-removed plasma at one time, and most of them had "visible benefits", such as improved attention, appearance and muscle tension.
"The theoretical basis of exchange transfusion is the experiment of' heterogeneous * * *'. In the classic' heterogeneous' experiment, scientists at Harvard University in the United States connected the blood vessels of two mice, one old and one young, and found that the blood of young mice can rejuvenate mice. " Weng Jiemin, a professor at the School of Life Sciences of East China Normal University, introduced.
That year, the research results were published in the journal Cell. According to the article, a protein named GDF 1 1 in the blood of young rats restored the muscle strength of mice. In 20 14, scientists from Harvard University published a paper in Science again, confirming that GDF 1 1 can promote skeletal muscle activity and neurogenesis and angiogenesis in the brain of aged mice.
In this regard, Weng Jiemin said that experiments show that richer or more active factors in young blood, such as GDF 1 1 (and of course other factors), may promote cell activity, proliferation or renewal, and may even promote reprogramming of aging individual cells to restore their activity, thus promoting individual health and delaying or alleviating aging.
The story of A Change of Blood is reversed: the old are not young, and the young are getting old.
When the elderly and beauty lovers cheer for the dawn, a new study published by the British magazine Nature News challenges this theory.
American researchers have found that the blood of young mice does not have the function of "rejuvenation", and inhibin in the blood of old mice may be the reason for promoting the aging process.
In order to study the influence of blood on the aging process, researchers at the University of California, Berkeley, let young mice exchange blood with old mice until half of the blood of one mouse comes from another, and then test the aging index of each mouse.
The researchers found that compared with the old mice that did not receive the blood of the young mice, the old mice that received the blood of the young mice did not significantly improve the aging index. However, young rats receiving the blood of old rats suffer from severe degeneration of tissues or organs.
They think that old rats have some benefits after receiving the blood of young rats, which may be because the blood of young rats dilutes the concentration of inhibin in the blood of old rats.
In addition, in Weng Jiemin's view, there are too many problems to be clarified to achieve the goal of "rejuvenation" through exchange of blood. First of all, whether blood exchange can inhibit human aging and how to inhibit it remains to be determined by further research results; Secondly, how much blood should be changed and how long it will last to be effective. These questions need more experiments to answer. "More importantly, it needs to be pointed out that the blood circulation between the old mice and the young mice in the' heterogeneous' experiment is untreated, and the problem of human blood exchange is much more complicated. The experiments reported at present are basically carried out on mice, not on higher animals, and many experiments, including human experiments, are needed to prove its feasibility. "
"Changing blood" is not something you want to change, but you need to face rejection and side effects.
Although the hope in the field of anti-aging is constantly dashed, it is still controversial whether young blood can "rejuvenate". But as human beings, you, me and him always hope that all this is true. But, to take a step back, even if all this comes true, is a blood transfusion really as beautiful as it looks?
"Of course not. First of all, we should match blood types to minimize rejection. The so-called blood type is only about the typing of antibodies in red blood cells and serum. In fact, there are many types of blood types, and platelets and white blood cells also have typing problems. " Weng Jiemin said that even if the above levels are consistent, that is, there is no incompatibility between antibodies of red blood cells, white blood cells and platelets, and there will be no hemolysis reaction, various antibodies or pathogens such as HCV and HBV in donor serum will pose risks to recipients.
Weng Jiemin said that due to the occasional risk of thrombosis, air embolism, heart failure and cardiac arrest, and the possibility of secondary infection, the indications must be strictly controlled. Moreover, some people are born with low immunity and cannot resist the immune rejection caused by exchange transfusion or bone marrow transplantation. Therefore, not everyone can exchange blood. In fact, it is easy to carry out related experiments on mice, because the genotype of experimental mice is the same, but everyone's genotype is different.
"I personally feel that it is impossible to completely exchange blood, because the cost of exchange blood is relatively high. Human blood accounts for 7%~8% of body weight, and blood is about 7000 yuan per 100 ml. The price of whole body blood exchange is too high. Moreover, the exchange of blood is not once and for all. The life span of blood cells in the body is relatively short, and the life span of factors that play a role in blood is even shorter. " Weng Jiemin said.
"This is just a commercial operation carried out by some institutions to achieve certain commercial interests." Han, director of the National Stem Cell Engineering Technology Research Center, said that blood exchange is a very complicated matter. In addition to the above problems, it also involves ethical issues. Whose blood is exchanged and where the blood comes from need strict channels. Umbilical cord blood does not involve ethics, but a small amount needs matching. Whether it has certain anti-aging effect needs further study. (Mei Qing)
Anti-aging products are mostly Mongolian medicine.
Everyone wants to be young forever. In recent years, anti-aging products have attracted people's attention and the market is hot. Even some wonderful anti-aging cheats have been widely circulated and admired. But are these cosmetics and health products that claim to delay aging really effective? The website of Life Science in the United States recently listed several common ingredients in anti-aging products, and invited experts to make a detailed analysis.
1. peptide. With the increase of age, the amount of collagen and elastin in human body gradually decreases, resulting in thinning of skin, loss of fat, sagging, fine lines and no longer smooth and firm. Peptide is a small fragment of protein, which can stimulate the growth of new cells and promote the healing of skin cells. However, Avona Poske, a plastic surgeon at the University of Pennsylvania in the United States, believes that it is still unknown whether the peptides in anti-aging products can work. Peptides are macromolecules, which may not completely penetrate into the deep skin if applied externally. Elizabeth Hull, a dermatologist at new york University Medical Center, believes that peptides can moisturize and make fine lines inconspicuous, but they cannot reduce wrinkles.
2. resveratrol. It is a plant compound, which is commonly found in wine. It is reported that resveratrol can prevent and treat chronic diseases such as diabetes and heart disease, but it is not clear whether anti-aging products made of resveratrol can produce similar effects. Hull suggested that if you want to supplement resveratrol, you should drink some wine.
3. Antioxidants. It can prevent free radicals from damaging cells, mainly including β-carotene, lycopene, selenium, vitamin C and vitamin E, which are widely found in fruits and vegetables, nuts and meat. Poske believes that some antioxidants, such as vitamin C and vitamin E, can effectively delay aging.
4.α- hydroxy acid. It can exfoliate and promote the renewal of skin cells, mainly including two kinds: lactic acid can remove dead skin and whiten skin; Glycolic acid helps to reduce wrinkles and make skin smooth and firm. Hull reminded that these two acids are irritating and photosensitive, and the elderly should pay attention to sun protection when using them.
5. Retinol. There is ample evidence that it can increase skin elasticity, reduce fine lines and delay aging, and is often added to skin care products. Hull reminded that pregnant women and women preparing for pregnancy should use products containing retinol with caution to prevent fetal defects.
6. sheep placenta. Fetoprotein is taken from the placenta of sheep after delivery, and is rich in raw materials necessary for promoting collagen, such as protein, various amino acids and trace elements.
7. Bird droppings. "Spice Girl" victoria beckham is an advocate of guano ointment, the main component of which is the excrement of a rare bird in Kyushu Island. Bird droppings will be disinfected with ultraviolet rays first, and the odor will be eliminated with rice bran.
8. Gold. Gold has been proved to have anti-oxidation, promote the formation of collagen, make nutrients quickly penetrate into the skin, make the skin bright, moist and moist, and achieve the effect of lifting and firming. In ancient Rome, gold was widely used to treat wrinkles, fine lines and inflammation. It is said that Cleopatra wears a gold foil mask when she sleeps every night. (hu zheng)
2. What can you eat to delay aging?
1. Corn
Corn contains dietary fiber, zeaxanthin and vitamin B, which can promote gastrointestinal peristalsis and expel toxins. Eating corn can also reduce blood lipids and cholesterol in the blood, which is also beneficial to blood cleaning, so it is beneficial to skin health. Therefore, women can eat more healthy food in whole grains-corn.
2. Black sesame
Black sesame contains vitamin A, vitamin E, lecithin, calcium, iron, chromium and other nutrients. Among them, iron and vitamin E are important components in preventing anemia, activating brain cells and eliminating vascular cholesterol. Most of the fat is unsaturated fatty acid, which has the function of prolonging life. Women often eat black sesame seeds, which is beneficial to beautify the skin and black hair and look young.
3. Cucumber
Cucumber is a common vegetable and a good product for delaying aging. Cucumber is rich in carbohydrates and vitamin E, which is very beneficial for nourishing the body and delaying aging. Cucumber enzyme in cucumber can improve biological activity and promote human metabolism. Therefore, women who want to stay young can often eat cucumbers.
4.cherry
Cherry is rich in sugar, protein, vitamin C, calcium, iron, phosphorus, potassium and other elements. Vitamin c can scavenge free radicals; Iron ions generate blood, promote blood flow and activate cells. Eating cherries is conducive to enhancing cell activity, making the face rosy, delaying aging and making people young and energetic. Cherry is a very suitable fruit for women.
5. honey
Honey is also a good choice for women to delay aging, especially dark honey. Black honey contains more antioxidant components, which can purify blood, protect cells and prevent diseases. Honey is also beneficial to skin care, which can promote skin regeneration and increase skin elasticity. Honey can be used as dessert and washed with warm water, which are all suitable ways to eat.
6.salmon
Deep-sea fish has the best anti-aging effect among fish. Salmon is a deep-sea fish with beauty and anti-aging effects, and astaxanthin contained in it has the function of scavenging oxidants in the body, so women can eat it properly. Eating salmon three times a week is very beneficial to the skin and body organs.