The "bleaching technology" in beauty salons has little effect on congenital black skin. I've seen many ladies bleach, but I haven't seen many that really turn white. I know one, which bleached well at first, and turned black again after a few months. It turns out that the so-called "bleach" is mostly highly toxic, and the most toxic component is mercury (mercury), and the principle of bleaching is to sink melanin in epidermis into dermis, rather than let melanin disappear. So whitening is only a superficial phenomenon. But the skin is constantly metabolized, so it won't be long before the skin color will become its original appearance again. If bleaching continues, melanin will sink again, and when melanin accumulates to a certain extent, it will turn black, making the skin darker than before. If this happens for a long time, it will make the skin suffer from "melanosis". Whitening at this time is not anti-disfigurement. This is not the most serious consequence. If you use bleach in large quantities for a long time, the poison in alkali will damage your skin, bones, internal organs and even your brain!
"Advantages" and "Excess" of Melanin
Melanin in the skin is synthesized by melanocytes. In melanocytes, tyrosinase synthesizes tyrosine into a substance called dopa. "Dopa" reacts with cysteine to produce melanin. Therefore, tyrosinase is the most critical factor in melanin synthesis. Subsequently, melanin is transported to epidermal cells and piled up like bricks to protect DNA from ultraviolet rays. Ultraviolet light can activate the activity of tyrosinase and promote the synthesis of more melanin. Therefore, the synthesis of skin melanin is a self-protection mechanism of human body. Tyrosinase is the key to synthesize melanin, so at present, most skin whitening products add tyrosinase inhibitors to cosmetics to destroy tyrosinase activity and achieve the purpose of reducing melanin. Hydroquinone was once the most widely used whitening agent because of its low price and good effect. Later, it was found that it was induced leukemia. Since 200 1, the use of hydroquinone in cosmetics has been banned in Europe. In addition, there are some chemicals that can also inhibit tyrosinase, some of which need mercury as a catalyst. Cosmetic companies are also committed to finding all kinds of "pure natural" whitening agents. According to their research report, some plant extracts also have the effect of inhibiting tyrosinase activity. "High-tech" is also used in whitening. In 2007, a French company developed a whitening product containing antisense oligonucleotides. According to the research papers of the company, whitening products containing antisense oligonucleotides can inhibit the expression of tyrosinase gene in skin cells, and the whitening effect can reach 30%. However, antisense oligonucleotides are generally not easy to enter cells. The real effect of this external application of "gene therapy" is questionable.
Painful peeling
Usually, the content of tyrosinase inhibitor in whitening cosmetics for external use is limited, and the "bleaching" effect is limited and the duration is not long. On the other hand, oral tyrosinase inhibitors take effect slowly. There is also a treatment called "chemical exfoliation", which can quickly remove melanin. Chemical exfoliation is to smear chemical reagents on the skin surface, corrode and exfoliate the skin, destroy the cells containing melanosome in the basement membrane of the skin, and make the skin thinner and whiter after regeneration. Generally, α hydroxy acid (also called fruit acid, AHA) is used for mild peeling, and the effect is relatively mild. Fruit acid peels off the outermost stratum corneum of the skin, which has a certain effect on wrinkle removal and freckle removal. However, trichloroacetic acid (TCA) used for moderate exfoliation will corrode and destroy the skin in a short time, causing great trauma, so it needs the doctor's operation in clinic. Deep skin exfoliation is carried out with strong corrosive phenol reagent. If the whole face peels off, it usually takes 2 hours for external application, and the patient needs to take painkillers. Some patients even need ECG monitoring at the same time, because phenol is in danger of inducing arrhythmia and other complications. The effect of mild and moderate peeling usually lasts only a few days to weeks, while the bleaching effect of deep peeling can last for months or even years. However, phenol used in deep stripping is a highly toxic chemical and carcinogen. There are also some physical methods to exfoliate skin, such as laser and cryosurgery. But they are generally only suitable for removing spots and moles, and wounds sometimes leave scars.
Edit this paragraph to analyze the chemical composition.
Products that can instantly whiten skin are likely to contain corrosive chemicals such as mercury and phenol. In a short time, the skin will be corroded and bleached, temporarily inhibiting the appearance of spots and traces on the skin surface, making the skin look very white. This forced and rapid whitening will peel off the protective film on the outer layer of epidermis and destroy the red blood cells of skin cells at the same time, leading to the decline of metabolic function, melanin deposition, thinning of stratum corneum and deterioration of skin condition. If you encounter ultraviolet radiation again, you will have problems such as allergies and redness. And this product is likely to be carcinogenic. The use of hydroquinone has been banned in Europe. Many people bleach their skin to hide birthmarks or repair pigment mutations caused by vitiligo. Skin bleaching is very popular in Asia and Latin America. But this kind of treatment often brings side effects.
Edit this section of danger
French scientists have also found that people who use skin bleaching products or whitening products will have serious side effects, especially African-Americans. The researchers followed up 46 people who used skin bleaching products. The results showed that two of them had adrenal insufficiency after using the bleaching product clobetasol, while others had hyperpigmentation, cracks similar to stretch marks and skin atrophy. In addition to skin bleaching, it also improves skin blackening and long shifts caused by poor maintenance. But for those with congenital dark skin and rough skin, the effect is not obvious. Many bleaching products contain highly toxic ingredients, which will not only damage the user's face, but also damage his teeth, stomach, brain and kidneys. Dermatologists remind beauty lovers that the metabolism of skin cells takes a long time. Therefore, beauty and skin care is also a gradual process, not "immediate" or "quick-acting".
Edit this misunderstanding about MJ's "skin bleaching"
A series of rare photos of Michael in the mid and early 1980s showed that there were white spots on one side of his face, forehead and ears, and his overall skin color was extremely uneven. 2. The skin color of Jackson family members is generally light (especially Michael's sister Latoya). At first glance, he looks like a Mexican, but he doesn't have the same disease as his younger brother, indicating that his family has a light skin color. According to the data, the Jackson family has a family history of vitiligo. Michael's medical records in a private clinic in California show that he really began to suffer from vitiligo from the late 1970s to the mid-1980s. This file was confirmed in the interview program of Opera Winfrey in 1993. His ex-wife, deborah rowe, was a nurse he met at the time of skin treatment, and she gave birth to his first two children. At that time, Michael discovered vitiligo while treating acne. Michael usually wears heavy makeup when he goes out. Wearing sunglasses and playing with an umbrella is not a quirk or a stunt, because Michael needs topical medicine to protect his skin from the sun. Today, Michael's real skin color may not be as white as we saw, but it can basically be considered as light brown, because vitiligo is more serious (basically spread to the whole body), and his whole face has been very different from that in the 1970 s. External drugs have made his skin look whiter. 5. 1993 was ordered to check private parts for allegedly molesting boys. Although no evidence was found in the end, Michael was confirmed to have severe vitiligo. The photo shows that his private parts, thighs and buttocks have a large area of vitiligo, and the area of white spots is huge (internal files of California police). 6. There is no complete bleaching technology in the world. Because bleaching in general only precipitates melanin in the skin, it will restore the original skin color after a long time, which is determined by genes. No matter how white it is, it will fade again with metabolism. To keep the skin fair for more than ten years, we must persist in bleaching for more than ten years. Medical evidence shows that this is equivalent to suicide. There are countless examples of skin ulceration, visceral lesions and even life-threatening due to bleaching transition. If it is bleaching once and for all, why is Michael the only one in the world? Why is such a revolutionary technology to change skin color unheard of in the world? Besides, it has been produced since the 1980s. 7. With regard to skin grafting, Michael did have a record of skin grafting once, but only once. 1984, he burned his head and neck while shooting a Pepsi advertisement, so he had a small area of skin grafting plastic surgery shortly after that year (because of this experience, Michael later donated a considerable sum of money to set up a medical emergency center "Michael Jackson Burn Emergency Center"), which led to the so-called skin grafting theory. However, the so-called whole-body skin grafting theory in the media is completely malicious, saying that whole-body skin grafting is medically impossible. So the whole body skin grafting theory is false.