The treatment of vulvar condyloma acuminatum should be based on the location and size of warts, so as to achieve the best therapeutic effect and reduce the occurrence of toxic and side effects. No matter what kind of treatment, there is the possibility of recurrence. It is best to use combination therapy, such as drug therapy or physical therapy combined with immunotherapy, which can reduce the recurrence rate.

First, medication.

1, 0.5% podophyllotoxin tincture: it is an effective component extracted from podophyllotoxin. First, apply vaseline or antibiotic ointment to the normal skin or mucosa around the wart, and then dip it on the surface of the wart with a small stick. However, this product has teratogenic effect and should not be used by pregnant women.

2.25% podophyllotoxin tincture: This product is crude podophyllotoxin and applied to the damaged surface of wart. This product has certain side effects, which can lead to nausea, vomiting, fever, abnormal sensation, leukopenia and thrombocytopenia, coma and even death. Because of its teratogenic effect, pregnant women should not use it, so it should not be delivered to patients for their own use and should be handled by medical personnel.

3.50% trichloroacetic acid solution: The interval of repeated medication should be 65438 0 weeks, and attention should be paid to protecting the surrounding normal skin and mucosa.

4. 5% imiquimod cream: Recently, it has been reported that this medicine is used for external treatment of condyloma acuminatum, with good curative effect and little side effects, and patients can apply it by themselves.

5.5% fluorouracil ointment: it can stimulate immunity and inhibit DNA and RNA synthesis, and can be used externally, but it should be noted that pregnant women are prohibited.

Second, surgical treatment.

Mohs operation is suitable for verruca, and it is suitable for patients who are ineffective in conservative treatment such as drug therapy. The operative method was Mohs operation. Smaller warts can be surgically removed or treated conservatively. If the skin lesion is infected, it will show redness and exudation. Surgical resection should be performed after the inflammation subsides.

Third, physical therapy.

1. Laser: Using carbon monoxide laser, it is very important to master the depth of treatment. Too shallow is easy to relapse, too deep is easy to cause wound healing and scar formation. Attention should be paid to bleeding and wound infection after operation.

2. Freezing: use liquid nitrogen or carbon dioxide dry ice to destroy the infected tissue and stimulate the immune response to this part. Cryotherapy has the advantages of simple operation, high efficiency and good patient tolerance, but it may cause scar formation and pigmentation.

3, electrocautery: use electrotome and electroacupuncture to treat, cauterize or remove warts.

Fourth, other treatments.

1, interferon contains a variety of protein and glycoprotein, and has antiviral, antiproliferative, antitumor and immunomodulatory activities. Can be used for intramuscular, subcutaneous or basal injection, 3 times a week, at least 4 weeks, usually 8~ 12 weeks. At present, there is no exact evaluation on the route of administration, dosage and therapeutic effect of interferin.

2. Patients can also be treated with drugs such as transfer factor and levamisole.