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How is the rabbit lip formed? Is it easy to have harelip when you are old?
How is the rabbit lip formed?

First, let's learn about rabbit lips. Rabbit lip is a congenital defect, which is medically called cleft lip or cleft lip. Cleft lip and palate can be unilateral or bilateral. This defect will not only affect the baby's appearance, but also affect the baby's pronunciation, swallowing and sucking. This disease is actually a polygenic genetic disease, and it is also related to some external environmental factors.

What are the causes of cleft lip and palate?

It is unfortunate for every family to have a baby with cleft lips, but modern medical conditions and plastic surgery conditions are very advanced, which can be recovered through surgery and the effect is still very good. The best operation time for a baby with cleft lip and palate is 3-6 months. The baby grows fast and recovers quickly after operation. The most direct example is Li Yan, Li's daughter, who has undergone surgery and now looks normal.

Is it easy for older babies to get harelip?

According to the research, if both parents are older, the probability of giving birth to harelip babies is higher than that of young parents, but a certain probability does not mean that older parents will definitely give birth to harelip babies, because the quality of sperm and eggs of older parents may decline, or such sperm or eggs may have certain defects to some extent. Therefore, if you want to have a healthy baby, it is best to be at an age suitable for pregnancy, and don't deliberately postpone the childbearing age.

In addition, pregnant women should not be picky about food during pregnancy, ensure the balance and comprehensiveness of all kinds of nutrition, insist on taking folic acid during pregnancy, keep a good mood and give birth to healthy babies. In fact, we don't have to worry too much about baby rabbit lips. Rabbit lips will not affect the baby's intelligence. On the contrary, God will open a door for you and close a window for you. Some babies with cleft lip are particularly smart and will behave differently from ordinary people in other ways. Of course, this situation can be completely corrected by surgery.

Welcome to read the comments.

Rabbit lip is a congenital defect, which is medically called cleft lip or cleft lip and palate. Rabbit lips don't want to affect not only the appearance, but also the baby's pronunciation.

The reason why the fetus has rabbit lips is 1. In most cases, the fetus has rabbit lips because the immediate or collateral relatives have similar deformities. That is because of genetic factors.

2. If the expectant mother is infected with a virus, such as flu or rubella, or suffers some kind of injury when she is pregnant for about two months, it will also cause the baby to vomit insects.

3. If the expectant mother is anemic or has diabetes during pregnancy, it will also lead to fetal cleft lip.

4. If the expectant mother is indirectly exposed to a lot of X-rays during pregnancy, affected by radiation, or the environment where the expectant mother lives is seriously polluted, the fetus will also have cleft lip.

5. If the expectant mother is particularly depressed in the first trimester, it may also lead to fetal harelip.

Is it easy to have harelip when you are old? This is not absolute. Some data show that the occurrence of hair loss is related to the reproductive age of parents, especially the higher the fertility of women, the higher the probability of conflicts between children, but this does not mean that older parents will definitely have harelip babies.

If you want to have a healthy baby, it is still recommended to get pregnant at the best age.

Rabbit lip is cleft lip and palate, which is a polygenic genetic disease caused by the interaction of genetic and environmental factors. Genetic factors play an important role in the pathogenesis of cleft lip and palate, accounting for about 20% to 50%. It is reported at home and abroad that the heritability of cleft lip and palate is about 70%, and the related genetic factors are family history, blood type and gender. The study of alleles of cleft lip and palate is a hot spot in recent years. At present, the candidate genes are TGFα, TGFβ3, BCL3, MTHFR, IRF6, RARA, F 13A and MSXl.

Environmental factors also play an important role in the occurrence of cleft lip and palate, including physical, chemical, biological and psychological factors.

Virus infection: Early pregnancy infection is an important inducing factor of cleft lip and palate. Some studies have pointed out that viral infection is seriously related to the occurrence of cleft lip and palate. The risk of fetal morbidity of infected mothers in early pregnancy is more than four times that of uninfected mothers.

Physics: Studies at home and abroad show that the exposure of pregnant women to electromagnetic radiation during the critical period of embryonic development (20-70 days after conception) is closely related to the occurrence of fetal congenital cleft lip and palate. Frequent exposure of pregnant women to radiation, ultrasound and microwave may be the inducement of cleft lip and palate.

Chemistry: Foreign surveys show that the mother's occupational exposure to certain chemicals is related to the occurrence of cleft lip and palate in newborns. The occupational exposure of 85/kloc-0 women in the first three months of pregnancy was investigated. The results showed that maternal occupational exposure to fatty aldehydes and glycol ethers was related to neonatal cleft lip and palate. Mercury, arsenic, lead, zinc, manganese, organic phosphorus, organic chlorine, organic solvents and heavy metal dust can all cause an increase in the incidence of cleft lip and palate.

Drugs: The teratogenic effect of drugs can not be ignored. Some drugs (hormones, vitamins, anticonvulsants, sedatives, analgesics, antibiotics, alkylating agents and aromatic hydrocarbons, etc.) are known. Improper or excessive use can induce congenital cleft lip and palate.

Living habits: When a mother smokes 20 cigarettes or more every day during pregnancy, the risk of cleft lip and palate will increase for her offspring, and passive smoking will also increase the risk of cleft lip and palate. Besides tobacco, alcohol is another known teratogenic substance. If the mother drinks a lot, the risk of cleft lip and palate will increase significantly.

Age-related: According to some epidemiological data, the incidence of cleft lip and palate is related to the reproductive age of parents. The higher the mother's childbearing age, the higher the incidence of cleft lip and palate deformity in offspring. It is generally believed that the incidence of cleft lip and palate is higher in the offspring of pregnant women over 35 years old. Studies have shown that pregnant women over the age of 39 are twice as likely to suffer from cleft lip and palate as pregnant women aged 25-29. This may be related to the gradual decline of female reproductive organs with age.

Mental trauma of pregnant women: stressful life events of mothers in early pregnancy will increase the risk of fetal cleft lip and palate, and the risk of non-syndromic cleft lip and palate of pregnant women who are nervous in early pregnancy is 3.25 times that of non-nervous pregnant women.

The so-called "rabbit lip" is the medical name of cleft lip or cleft palate, which is collectively called congenital cleft lip and palate in children. So how did cleft lip and palate come into being? What is the cause of cleft lip and palate in children? Is congenital cleft lip and palate related to advanced pregnancy?

healthybaby

What is congenital cleft lip and palate? Congenital cleft lip and palate is the upper cleft lip formed by cleft lip and palate in embryo, which is characterized by unilateral or bilateral, partial or total split, making the upper lip into two or three flaps, commonly known as "rabbit lip" and medically called cleft lip. If the maxillary cavity and small tongue also split, it is medically called cleft palate. Medically, it is called congenital maxillofacial deformity.

Congenital cleft lip and palate is the most common congenital malformation in oral and maxillofacial region, with an average of 1 child with cleft lip and palate in every 700 newborns. Cleft lip and palate not only seriously affects facial beauty, but also directly affects development because of the communication between oral cavity and nasal cavity, which often causes upper respiratory tract infection and otitis media. Because of the difficulty in sucking milk, the child is obviously malnourished, which causes serious psychological trauma to the child and parents.

Congenital cleft lip and palate

How is congenital cleft lip and palate formed? Many folklore says: rabbit lips are eaten by mothers when they are pregnant; Or what ditch has been dug at home; It is also said that scissors were used when cutting clothes on the bed, which collided with the "fetal god". These are legends without scientific basis. Let's just listen to the stories.

In fact, a large number of medical studies have confirmed that congenital cleft lip and palate is a congenital malformation caused by fetal facial development disorder due to some pathogenic factors from the fourth week of pregnancy to the 10 week. After years of genetic and pathological research, experts know that the causes of cleft lip and palate are as follows:

1, genetic factors

A large number of genetic studies have proved that fetal cleft lip and palate is a polygenic disease, and 20% to 30% of children have dominant genetic factors.

About 20% children with cleft lip and palate have a genetic history. General 1 The probability of fetal cleft lip and palate is 1/600. If 1 fetus has cleft lip and palate, the probability of cleft lip and palate in the second fetus will increase several times, reaching 3/ 100. For example, a baby's brother or sister has fetal cleft lip and palate defects, then the probability of this baby's cleft lip and palate will be 30 to 40 times that of other normal babies; So it is very common to see similar deformities in relatives of patients.

Heredity, gene

2. Infection and injury

In the early pregnancy (usually about 2 months), the mother was infected with viruses, such as influenza virus, rubella virus, cytomegalovirus, Toxoplasma gondii, etc., or suffered some serious injuries, which may be the cause of cleft lip and palate. This is why we often ask pregnant women to do a virus screening called "prenatal and postnatal care" at an early stage.

3. Taking certain drugs and receiving radiation during pregnancy:

My mother took sedatives and some antiepileptic drugs and hormonal drugs during pregnancy. In addition, during pregnancy, my mother received a large dose of X-rays. These may cause fetal maxillofacial deformities.

4. Age factor

This is a question to ask. Relevant data show that the risk of fetal cleft lip and palate increases with the age of both parents. Compared with a 30-year-old mother, the risk of fetal cleft lip and palate increases by 20%. Between 20 and 50 years old, the risk of fetal cleft lip and palate increases 12% with the increase of father's age. Of course, if one of the parents is very young, this rule may not hold.

5. Environmental factors

environmental factor

Environment is the most important influencing factor of teratogenesis in children's embryo; Mother in the early pregnancy (3 months ago) one of the following problems, may lead to fetal cleft lip and palate:

? Vitamin deficiency during pregnancy, especially folic acid deficiency;

? Long-term exposure to pesticides, long-term tobacco and alcohol stimulation, etc. It may cause gene mutation and a series of fetal cleft lip and palate;

? Endocrine disorder, intense mental stimulation, physical injury, etc. ;

? Severe vomiting, anorexia and partial eclipse in the first trimester lead to malnutrition.

How to prevent congenital cleft lip and palate? prevention first

Prevention is the key to control the occurrence of cleft lip and palate, and the key to prevention lies in the implementation of various preventive measures in the first trimester. In the second and third months of early pregnancy, we should try to avoid the inducing factors we introduced above. Earlier, we also introduced to parents that congenital cleft lip and palate is the result of the combined action of environmental factors and genetic factors.

1, folic acid in early pregnancy:

Studies have shown that insufficient folic acid intake or abnormal folic acid pathway genes may lead to congenital cleft lip and palate, and may also lead to other problems in embryos, such as heart malformation and neural tube malformation. Timely intake of folic acid can promote the fusion of upper lip and palate. At the same time, folic acid can also avoid the intake of viruses or some toxic substances.

folic acid

2. Avoid heredity and genetic problems:

Cleft lip and palate is a polygenic disease with a certain genetic tendency. If one parent has cleft lip and palate, his offspring will have a higher probability of cleft lip and palate than ordinary families. So we must avoid consanguineous marriage. If 1 fetus has cleft lip and palate, try not to have a second child to avoid increasing the risk of cleft lip and palate.

3. Avoid virus infection and radiation:

Try to avoid colds and viral infections in the first trimester; Sedative and antiepileptic drugs should not be taken orally during pregnancy. Avoid radiation, including computer radiation. Take necessary protective measures.

Yes, that's right! Faye Wong, for example, is past the age of having children! (If you are over-aged, the child born is either this problem or that problem) Qiuguo? Qiuhuluwa

How is the rabbit lip formed? Is it easy to have harelip when you are old?

The causes of rabbit lip formation are closely related to genetic factors and environmental factors. After the fifth week, the normal fetus began to gradually merge with some embryonic processes to form a face. If it fails to develop normally, it may be deformed, including rabbit lip and cleft lip.

Then the reasons for the formation of rabbit lips are as follows:

1, due to parents. The main cause of harelip comes from parents. If pregnant women do not properly supplement folic acid in the first three months, they may also give birth to children with rabbit lips. In addition, some pregnant mothers are elderly pregnant women, which will also increase the chances of giving birth to harelip babies. Therefore, it is suggested that female friends must choose the best age to get pregnant in order to improve the chances of giving birth to a healthy baby.

2. Eating habits. Many pregnant mothers will have morning sickness in the first trimester. Some pregnant mothers have severe morning sickness for a long time and have no appetite to eat. After two or three months, nutrition can't keep up. If the intake of vitamin A in the early pregnancy is too small, or the body is deficient in vitamin A, it is easy to have rabbit lips when pregnant with the mother's treasure. In addition to nutritional problems, pregnant mothers smoke, drink, dye their hair and get their nails done. During pregnancy, it may cause fetal cleft lip and increase the chance of fetal malformation.

3. Living environment. Some prospective parents plan to have children, or pregnant mothers still work in ionizing radiation areas and are often exposed to X-rays or toxic gases. It is also easy to cause fetal malformations, including rabbit lips. Therefore, it is recommended that couples who are preparing to get pregnant stay away from these places three months in advance. It is best to choose a place with good environment and fresh air to recuperate, prepare for pregnancy and add points for the birth of a healthy baby.

As for getting older, is it easy for children to get harelip? This is not absolute. It depends on the individual's physique and whether the family has genetic genes, but if both husband and wife have a comprehensive examination before pregnancy, they will definitely find out, so the pre-pregnancy examination is also very necessary.

If pregnant, pregnant mothers should pay more attention to it, and it is very important to do pregnancy tests on time, especially four-dimensional color Doppler ultrasound, thalassemia screening, Down's screening, glucose tolerance and so on. At the same time, we should pay attention to balanced nutrition, count fetal movements and observe fetal movements at any time. Keep a happy mood every day, do not use drugs indiscriminately, stay away from second-hand smoke and alcohol, and develop good living habits. For the sake of the health of the fetus, it is worthwhile for pregnant mothers to restrain some of their bad habits for ten months and give birth to a healthy baby.

This is not necessarily the case.

First of all, thank you for inviting me.

Rabbit lips are commonly known as rabbit lips.

There are many reasons for harelip, including heredity, external stimulation, virus infection, physical factors, chemical factors and so on.

Lack of vitamins and folic acid during pregnancy may lead to rabbit lips;

Pregnancy with hormones can also affect fetal cleft lip and palate; Rubella virus infection during 8- 12 weeks of pregnancy will affect the occurrence of cleft lip and palate;

Pregnancy can be exposed to radiation,

Stimulation such as alcohol and tobacco will also affect rabbit lips.

There is another proverb in our hometown:

Eating rabbit meat during and before pregnancy,

And the chance of rabbit lips.

Of course, this is a way of saying.

There is no scientific evidence to support it.

As for your question, is it easy to have children when you are old?

According to some epidemiological data, the incidence of cleft lip and palate is related to the reproductive age of parents. The higher the mother's childbearing age, the higher the incidence of cleft lip and palate in offspring.

It is generally believed that the incidence of cleft lip and palate is higher in the offspring of pregnant women over 35 years old.

Studies have shown that pregnant women over the age of 39 are twice as likely to suffer from cleft lip and palate as pregnant women aged 25-29.

This may be related to the gradual decline of female reproductive organs with age.

Mental trauma of pregnant women:

The stress life events of mothers in early pregnancy will increase the risk of fetal cleft lip and palate. The risk of non-syndromic cleft lip and palate in pregnant women with stress response in early pregnancy is 3.25 times that of pregnant women without stress response.

The risk of elderly women is relatively high, and the risk of fetal malformation is relatively high.

Rabbit lip (cleft lip and palate), as a congenital genetic disease, has no exact cause at present. Most suspects are related to heredity, nutrition, endocrine or infection, trauma, etc. Some data show that the incidence of elderly women is higher than that of school-age women, but this may be caused by many reasons. After all, older women bring many risks, whether they are fetuses or adults.

It is suggested that pregnancy preparation should be done well in advance, and both husband and wife should quit smoking and drinking, increase physical exercise appropriately, supplement folic acid and related vitamins, and work and rest reasonably. Pay more attention during pregnancy, especially all kinds of pregnancy screening must be done, which can screen out many possible congenital malformations or chromosomal abnormalities to the greatest extent.

If you are really too old, not short of money or really have congenital chromosomal diseases, it is recommended to do the third generation of test tubes, and PGD screening can filter out great risks.

Finally, children with congenital malformation or congenital diseases such as Down syndrome are waiting for special treatment that they can't get rid of all their lives. I really hope that every parent should do all the work seriously. The new life is worth looking forward to and taking seriously.

This kind of opportunity is still very rare, generally not. I have harelip, which is caused by smoking and drinking during pregnancy.