The main difference between work gloves 400 and 600 lies in size and quality. Details are as follows:

1. Size: 400 type work gloves are relatively small, suitable for women's hands, while 600 type work gloves are relatively large, suitable for men or people with large hands.

2. Material: 400 model gloves are made of cotton and linen, and 600 model gloves are made of pure cotton.

To sum up, the choice of work gloves depends on the specific use needs and the size of hands.