Hotel slippers can be worn out, but it is generally recommended not to wear out for too long for the following reasons:

1. Hotel slippers are generally disposable. Wearing them may damage shoes, which is not cost-effective.

2. If you travel for a long time, it may be uncomfortable to wear hotel slippers. If you want to run a long distance, you'd better put on your shoes.

The above suggestions are for reference only. You can try them if you want.