The incidence of congenital heart disease in children is about 4 ~ 8‰, which is a common congenital disease. It is found that genetic factors play a certain role in the occurrence and development of congenital heart disease. For example, the heritability of atrial septal defect is 57-60%, and the risk of recurrence of siblings and children of proband is 2.5-4.6%. The incidence of ventricular septal defect in Asia is 1.2-3. 1, and its heritability is 43-55%. The recurrence risk of the proband's siblings is 3.3-4.4%, and the recurrence risk of their children is 3.7-4.0%.

The most common congenital heart disease related to heredity is congenital heart disease with other organ abnormalities, such as polysplenia syndrome, in which 100% is accompanied by congenital heart disease, chromosome diseases such as 2 1 trisomy syndrome, 50% of patients are accompanied by congenital heart disease, and 40% of Turner syndrome can be accompanied by congenital heart disease.

Many people think that patients with congenital heart disease have no danger of giving birth after surgery, just like normal people. This view is not comprehensive. They only pay attention to the endurance of the heart and ignore the heredity of the disease. Therefore, if you want to fully understand the influence of congenital heart disease on marriage and childbearing, you can go to the designated premarital examination unit or go to the cardiology department for examination according to your own heart disease type, such as color B-ultrasound of the heart. Follow the doctor's advice and have genetic counseling.