After Caesar died, Anthony ruled Rome. When he visited the eastern colonies, he sent someone to convey the order to summon the queen in Talema, Asia Minor. In order to win the favor of the nouveau riche, she specially dressed up and showed fascinating charm. This beautiful woman who made Anthony drool as early as Rome soon fell into his arms. Anthony resolutely gave up his mission to the East and returned to Alexandria on the Queen's luxury yacht. From then on, the two men were inseparable, loving each other and hanging out in the Egyptian palace for five long years. Later, Anthony married Octavian's sister against his will, but soon found an excuse to return to the East, abandoned his wife and married Cleopatra.

This violation of Roman marriage custom was naturally condemned by public opinion. He gave it to Cleopatra, whom he regarded as the "queen of kings", without authorization, which aroused the anger of the Romans. At Octavian's instigation, the Roman Senate and the Civil Assembly revoked his position as consul and deprived him of all his powers.