Botulinum toxin, said to be the most poisonous substance in the world, has flowed into the faces of 6,543,800+600,000 American women in the past year. Even Americans say these are "crazy" women. Their madness stems from their desire for youth. But it's not crazy. The US Food and Drug Administration (FDA) revealed that it will officially approve botulinum toxin for wrinkle removal. Authorities generally predict that there will be a "beauty storm" in the United States this spring. Allergan Company in California, USA, which produces and sells this toxin called Botox, said that it will spend 654.38 billion to 200 million dollars to launch a powerful promotion campaign in the next year, which may be even larger than when Viagra came out a few years ago. Botulinum toxin is a young medicine in the eyes of women. Inject a small amount of botulinum toxin into the forehead or brow, wrinkles and crow's feet will be miraculously erased, so that the good thing of "one shot works" naturally makes it irresistible to love beauty. This kind of operation, which can be simply summarized as "poisonous needle wrinkle removal", costs 500 to 1000 dollars at a time, and the wrinkle removal effect can only last for several months. Re-injection is needed every four months, otherwise wrinkles will climb on your face again. That's it, American women are still flocking. In recent years, "poisonous needle wrinkle removal" beauty has become one of the fastest growing industries in the United States. According to the statistics of the American Society of Aesthetic Surgery, its turnover has increased by more than 20 times in the last five years, and the total sales last year reached 3 1 100 million US dollars. In 2000, "needle lifting" surgery accounted for 19% of the total cosmetic surgery in the United States, while the proportion of breast augmentation was only 3.5%. It is predicted that the "green light" of FDA will further stimulate the sales of this industry to climb to $6,543,800 billion in 2006. It is purely coincidental to find the magical wrinkle removal effect of botulinum toxin. Botulinum toxin comes from Botox, which is very toxic. There are seven kinds of botulinum toxin, of which type A is weak, which can relax local muscles, but it will not enter the brain from blood vessels. It has long been regarded as a means of "fighting poison with poison" to treat strabismus and other diseases. During 1987, a female doctor in Vancouver, Canada accidentally discovered that the purified botulinum toxin A can paralyze facial muscles and eliminate wrinkles. Her first report was published in 1990. The FDA has always banned the promotion of anti-aging and wrinkle-removing effects of botulinum toxin A, but it has long been approved as a drug for the treatment of strabismus. In fact, this has caused the United States to ban "poisonous needle wrinkle removal". As long as there is no publicity, this operation will be left unattended. As the FDA is about to lift the ban, various concerns begin to appear. The first is technical. The dose of botulinum toxin A required for wrinkle removal is extremely small, which is basically harmless to human body. It is said that this is also the main reason for the FDA to give a "green light". However, this operation is not without side effects. If the dose is not well controlled, it may lead to drooping eyelids and eyebrows. The beauty industry in the United States is worried that after the management is relaxed, the profit of the "poisonous needle wrinkle removal" beauty industry will be higher, and some doctors with no background and experience may change careers and squeeze into this road. More discussion focuses on culture. "Poison needle wrinkle removal" can make the face smooth and even, and it can also lead to stiff skin. Ruman, director of the musical Moulin Rouge, complained that many Hollywood actresses went too far during the operation, and as a result, they "didn't know how to move their faces". A columnist asked: Does a mask-like face have to look good without expression?