Cell nutrient solution is a safe and effective method. Use autologous cells and autologous growth factors to replenish a large number of missing cells and promote skin regeneration and repair. Cell nutrient solution can increase the quantity and quality of fibroblasts, promote the secretion of nutrients such as collagen, hyaluronic acid and elastic fiber, and fundamentally eliminate wrinkles. This method is cultivated by the national GMP biological laboratory, and has reliable source and quality assurance. In contrast, stripping technique is a common plastic surgery method, which requires surgical cutting and tissue separation for subsequent plastic surgery. Although the stripping technique can expose the tissue in the operation area, it may have the problems of operation risk and long recovery period. Therefore, considering comprehensively, cell nutrient solution is a better choice.