If you get breast cancer abroad, you will definitely test whether there is a family gene. If so, the attending doctor may suggest preventive resection. However, genetic testing has not been popularized in China, mainly because compared with Europeans and Americans, Asians carry fewer mutant genes, with 2.5% in Nordic Jews and only 0.5% in Asians. In Asian breast cancer population, only 4% can detect the mutant gene, which may be 1 1% in Europe and America. For people over the age of 35, the risk of breast cancer in Asia may reach 15%, and that in Europe and America may reach 23%, which is still very different. Familial and hereditary breast cancer are two concepts. Familial breast cancer means that two first-degree or second-degree relatives have breast cancer, and about 30% to 40% of them are found to carry mutant genes, but it does not mean that everyone carries them and does not have the ability to spread. Hereditary breast cancer carries a mutant gene, which will be passed on, so the risk of carrying the mutant gene in the next generation is very high. Because there are no treatment guidelines in China, even if the mutant gene is detected, doctors often dare not do mastectomy for fear of legal risks. From the technical point of view of plastic surgery, preventive mastectomy is no problem. After mastectomy, many can be reconstructed directly. After mastectomy, the silicone prosthesis will be replaced, so that she can quickly integrate into this society. We have done a survey. Compared with patients who have undergone total mastectomy and no reconstruction, patients who have undergone prosthesis or breast-conserving surgery have significantly faster postoperative and psychological recovery and integration into society. Some people worry that breast reconstruction will increase the risk of breast cancer or other diseases, but in fact, many experiments and surveys have found that the incidence of breast cancer in the general population with implants is not higher than that in the population without implants. There is no difference between the two surveys, so this kind of worry is unnecessary. After one-stage resection, radiotherapy and chemotherapy are all completed, and there is no sign of recurrence, so breast reconstruction can be done. Some patients are at high risk, and it may be suggested to do secondary plastic surgery after two or three years when there is no problem.