The primary consideration of clinical trials is that they must meet ethical requirements and must not harm the interests of patients, otherwise the trials will not be approved by the ethics committee, let alone carried out. Unlike the "jury" in foreign courts, ethics committees are not composed of doctors or medical personnel, but are generally composed of people from all walks of life. Therefore, the basic interests of patients participating in clinical trials have been protected.

In addition, at present, most clinical trials do not directly use ineffective placebos as controls, but set up control groups for treatment, and generally adopt the currently recognized standard treatment. In other words, even if patients are divided into control groups, researchers will not let patients' conditions develop at will.

At the same time, hospitals and departments that can carry out clinical trials are generally clinical trial bases with strong comprehensive strength and strict examination and approval by the State Administration of Medical Supplies. The general research doctor is also a senior specialist with rich experience in diagnosis and treatment of this disease. If the patient has any discomfort during the treatment, he can communicate and consult with the research doctor, and once there is a need for emergency treatment, he can deal with it quickly.

As the saying goes, every drug has side effects, but every scientifically designed clinical trial is to explore the effective dose of new drugs on the basis of ensuring "safety", which is the key.

Generally speaking, if the patients meet the conditions for admission and the doctors of the research group evaluate that the patients can be admitted, then the relevant drugs and examinations after admission are free, and there will be some additional transportation subsidies. The situation of each project is different, and the doctors of the research group will explain the whole project one by one before signing the informed consent form.