Suggestion: 1. In recent years, tumor has become one of the main causes of acquired deformity or defect in maxillofacial region. Maxillofacial deformities caused by tumors themselves are mostly benign tumors, and most of them are congenital malformations, such as hamartoma, tubular tumor and neurofibroma. A few non-congenital tumors, such as jaw cysts and odontogenic tumors, can cause asymmetric deformity due to tumor development and compression. For malignant tumors, most of them are caused by different degrees of defects or deformities after surgical treatment. The later the disease stage is, the more tissues are removed, and the greater the deformity defect is. In addition, radiotherapy can also lead to tissue defects, especially radiation osteonecrosis, or growth inhibition and tissue atrophy caused by radiotherapy. 2. Injuries With the rapid development of China's transportation industry and the further improvement of modernization level, oral and maxillofacial deformities and defects caused by traffic accidents are increasing day by day. Followed by life trauma, life trauma, including childhood falls, is the main cause of unilateral (or bilateral) temporomandibular joint injury, partial jaw (or micrognathia) deformity, sometimes accompanied by limited mouth opening, resulting in true temporomandibular joint stiffness. Thirdly, nonspecific inflammation of inflamed soft tissue can cause deformity, but generally it will not cause tissue defect. Inflammation of maxillofacial bones, due to bone necrosis, dissolution or separation, can often cause maxillofacial deformities in different degrees. Deformity can be caused not only by bone defect itself, but also by the destruction of the growth and development center of jaw, such as condyle in childhood, which makes one jaw develop abnormally. Specific inflammation, including syphilis and tuberculosis, can lead to defects and deformities of soft and hard tissues in maxillofacial region. Gum swelling in advanced syphilis can lead to palatal perforation; Syphilis can also cause the next generation of nasal deformities, which is a typical saddle nose. Due to the continuous improvement of medical and health care conditions, gangrenous stomatitis has become less and less common, because it can cause necrosis of large areas of soft tissue or bone tissue, and often leads to tooth closure due to severe scar contracture, resulting in pseudo temporomandibular joint ankylosis, so it should still be paid attention to. The overall treatment of Xijing Hospital includes the latest achievements in recent years, such as orthognathic surgery, distraction osteogenesis, microsurgery, maxillofacial repair, implant technology, computer-aided design and manufacturing technology, etc., and its complexity and danger are the first in the world. The hospital has now deployed elite troops to form an expert group to ensure the success of the operation. According to Professor Liu Yanpu, Director of Maxillofacial Surgery, the hospital will reconstruct Wang Na's face through three stages: zygomatic traction, second-stage bone transplantation to reconstruct the midface bone, and third-stage tooth implantation to restore chewing function. In the meantime, the hospital will also redesign Wang Na's face through computer 3D technology, and strive to make the reconstructed face no different from ordinary people. The high cost of surgery is unbearable for a poor family anyway. At present, the hospital is calling on the staff of the hospital to raise funds. At the same time, Dean Zhao Yimin also implored the whole society to lend a helping hand to this rare "pothole girl" in the world. I believe that in the near future, a hopeful Wang Na will appear in front of the public with a brand-new face.