1. Men who are positive for hepatitis virus (HBV or HCV) serological indicators, have a history of liver cirrhosis or chronic hepatitis, and are over 35 years old can be considered a high-risk group, and regular monitoring of them is The main way to detect early-stage small liver cancer.

2. Alpha-fetoprotein (AFP) and B-ultrasound are currently the most sensitive, convenient, and economical diagnostic methods for small liver cancer screening.

3. For those who are positive at low concentrations of AFP, AFP heterogeneous detection can be supplemented, and for those who are negative for AFP, other liver cancer markers can be detected, which is beneficial to the qualitative diagnosis of early liver cancer.

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4. The advancement of imaging technologies such as ultrasound, CT and magnetic resonance imaging has made it no longer difficult to diagnose small liver cancers below 1 cm. New contrast agents have further improved the sensitivity of ultrasound and MRI, and contrast-enhanced ultrasound can help evaluate the vascular distribution and blood supply of liver cancer. Tissue-specific NMR enhancers (such as superparamagnetic iron oxide) can also further improve the detection rate of small liver cancer. In addition, the development of three-dimensional imaging technology also provides new means for diagnosing small liver cancers.