Botox wrinkle removal effect is very ideal, which is caused by facial expression muscles. Botox wrinkle removal reduces wrinkles by blocking the contraction of facial muscles. Generally speaking, the maintenance time of the first injection in botox wrinkle removal effect will be shorter, generally 6- 12 months, but the maintenance time of the second injection will be very long, so it can be repeated. Therefore, there is no doubt about the effect of Botox wrinkle removal. The wrinkle removal effect of Botox is also related to the hospital you choose and the doctor's skills, so you must choose a regular one when choosing a hospital.