It covers the parts that need skin grafting with a special material, which will automatically stretch the affected parts into a skin state similar to the body.

Stretching is better than skin grafting.

The details are as follows:

Active "artificial skin" successfully developed by Stomatological Hospital of Fourth Medical University. Correspondent Tian She

In case of a patient with extensive burns, the doctor only needs to take out an "artificial skin" from the refrigerator and stick it on the damaged part of the patient, and the wound can be healed. This dream came true in the Fourth Military Medical University. Yesterday, Professor Jin Yan from the Stomatological Hospital of the Fourth Medical University demonstrated this magical active "artificial skin".

Only the United States has mastered this technology in the world, and four medical universities in China are the first.

At yesterday's exhibition, experts carefully held out a Petri dish with a diameter of about 20 cm, and there was a milky white film in the Petri dish. This is the active "artificial skin" called "tissue engineering skin" by the medical community, and it is also a major special research project of organization and organ engineering under the National 863 Plan.

At present, only the United States has mastered this technology in the world, and it is the first of the four major medical universities in China. Not long ago, this achievement obtained the product registration certificate issued by the US Food and Drug Administration.

According to Professor Jin Yan, this kind of "artificial skin" has dermis and epidermis, contains living cells, and can "grow" quickly with the original skin, just like autologous skin, without immune rejection, and has the function of normal skin.

Professor Jin Yan said that there are about150,000 burn and ulcer patients in China every year, of which about 3.5 million people need skin transplantation. Because there is no alternative skin source, autologous skin transplantation is often used in treatment. "This method of robbing Peter to pay Paul will not only cause new trauma, but also have the problem of no wall to dismantle."

Skin tissue the size of a nail can grow skin the size of a football field.

Active "artificial skin" is hardly limited by the source of donor skin. Professor Jin Yan told reporters that the raw materials for producing active "artificial skin" mainly come from surgical excision and other discarded healthy human skin tissues, from which the most critical components are separated, and then through the process of culture, it only takes 10 days to form active living tissue skin. "The image point is that it is planted in a Petri dish. A skin the size of a fingernail can be made into a skin the size of a football field. "

"The clinical application is also very simple. As long as artificial skin is attached to the affected area, the repaired wound will eventually be replaced by the human body's own tissue." Professor Jin Yan told the reporter that transplanting active "artificial skin" not only has low immune rejection, but also has fast healing time, which can reduce scar formation. He said that active "artificial skin" is widely used, which can be used to repair skin burns, ulcers, wounds and skin defects, and can also be used for the detection and screening of cosmetics or drugs. At present, it has officially entered clinical application.

It is understood that active "artificial skin" is the first successful product of tissue engineering research in China, and it has completely independent intellectual property rights in China. Since the launch of the 1998 research project, it has been supported by major national special projects such as the Tenth Five-Year Plan, the Eleventh Five-Year Plan and the 863 Plan, obtained four national invention patents, and formulated the first domestic product standard for tissue engineering. Its successful development is a milestone, which indicates that China's tissue engineering research has entered the era of industrialization and has great medical clinical significance.

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What is "artificial skin"

"Artificial skin" is a skin substitute artificially developed in vitro by using the principles and methods of engineering and cell biology. It is used to repair and replace defective skin tissue. According to different components, it can be divided into pure artificial dermis and active composite skin with epidermal cell layer.

After 1980s, some scientists have developed a variety of artificial dermis, such as acellular dermal matrix derived from allogenic or xenogenic (pig) skin, spongy collagen membrane with freeze-dried collagen as the main raw material, hyaluronic acid membrane and polylactic acid membrane. Its basic feature is that it can induce the infiltration and growth of autologous tissue cells to form a new dermal-like tissue with regular structure, thus reconstructing the dermis.

Since the 1990s, the medical community has successfully applied composite skin to the repair of large-area deep burn wounds, saving the autologous skin source of the injured and improving the on-site treatment rate. However, due to the high manufacturing cost of composite skin, the survival rate after transplantation is only about 50%, and it will take some time to be widely used in clinic.

Although the research of artificial skin in China started later than that in western developed countries, it has been highly valued by the state in recent years.

With the development of medicine, people believe that in the near future, artificial skin can be placed on the counter of "shops" like machine parts, replacing damaged skin tissue, changing the high dependence of burn wound repair on autologous skin source, and improving the success rate of burn treatment and the quality of wound repair.

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