It is not difficult to see from some cases that the death of ovarian cancer accounts for the first place in all kinds of gynecological tumors every year, which poses a serious threat to women's lives. Under normal circumstances, surgical resection is the main treatment, but due to the lack of effective diagnosis methods in the early stage of ovarian cancer, the effect of later surgery is often poor. Next, let's take a look at the successful cases of stage 4 ovarian cancer.
Materials and methods, treatment methods
Routine blood tests, coagulation time, chest X-ray, electrocardiogram and B-ultrasound were performed before operation. Diazepam 10mg was injected intramuscularly 30 minutes before operation. If cisplatin chemotherapy is selected, intravenous hydration will be performed after operation.
Let the patient lie flat on the operating table, prepare the skin of groin and perineum, fully expose the operating site, establish venous access, and puncture femoral artery cannula percutaneously, first do abdominal aorta-iliac artery angiography, then do bilateral internal iliac artery angiography. 50 mg of pirarubicin was dissolved in 60 ml of 5% glucose injection, 60 mg of cisplatin and 400 mg of cyclophosphamide were dissolved in 60 ml of 0.9% sodium chloride solution, respectively, and then interventional chemotherapy was performed via catheter internal iliac artery. If bilateral internal iliac artery chemotherapy is needed, the above drugs can be divided into two parts and injected bilaterally. Pay attention to ECG monitoring during operation and observe the changes of vital signs of patients.
After operation, the patient must stay in bed, compress the puncture site with sandbags for 6 hours, and brake the lower limbs at the intubation side for 24 hours. Pay attention to the bleeding at the puncture point, the color of the dorsal artery of the foot and the skin on the surgical side, and whether there is pain in the lower limbs. And intravenous drip of sodium thiosulfate, 2 to alkalize urine, so that the patient's urine volume is greater than 65438 050 ml per hour.
Postoperative follow-up because tumor chemotherapy is a chronic process, patients need to actively cooperate to achieve satisfactory results. The first three courses of interventional chemotherapy were 1 time per month, changed to 1 time after 3 months of stable condition, changed to 0.5a 1 time after 2 years, and were followed up for 4 years.
Routine blood test every week 1 time. If the white blood cells are less than 3.0× 109 per liter and the platelets are less than 80× 109 per liter, give blood-generating drugs to strengthen nutrition and ensure the smooth progress of chemotherapy.
Regular B-ultrasound examination, to observe whether the lump shrinks or increases, so as to adjust the treatment medication.
Pay attention to the combination of work and rest, ensure adequate sleep and maintain a good attitude.
result
After three courses of treatment, the symptoms of abdominal pain, abdominal distension and ascites disappeared in 4/kloc-0 cases, and the tumor shrank in 35 cases by B-ultrasound. Among them, PR 16 cases and MR 19 cases. 2.2 Adverse reactions and measures
Seven patients had symptoms such as flushing, dizziness, palpitation and perineal tingling during the injection of pirarubicin. After oxygen inhalation and catheter injection of 2% lidocaine 50mg, the drug injection speed slowed down and the symptoms disappeared about 10min.
Puncture point bleeding 1 case.
Abdominal pain, nausea and vomiting occurred in 2 cases. After taking a few milligrams of ondansetron and acupuncture Neiguan, Hegu and Zusanli, the symptoms were relieved after1h.
1 case of postoperative palpitation and chest tightness. After ECG monitoring, oxygen inhalation and myocardial nutrition, the symptoms disappeared after 48 hours.
Postoperative abdominal pain occurred in 2 cases, and the urine volume was less than 800ml at12 h. Furosemide and iv were given to supplement the fluid volume to make the urine volume greater than 150ml/ h.. 3 discussion
Injecting high-concentration anticancer drugs directly into tumor blood supply artery can increase the drug concentration in tumor focus. The drug concentration in tumor focus is many times higher than that of systemic intravenous administration and many times higher than that of intraperitoneal administration. Intra-arterial chemotherapy of tumor blood supply is beneficial to improve the curative effect and shorten the course of treatment. After intra-arterial administration, the drug concentration in peripheral blood was also determined. Intra-arterial administration includes intravenous administration and intraperitoneal administration. Therefore, intra-arterial administration of drugs in tumors has high concentration, long duration, light systemic toxicity and side effects, and postoperative nausea and vomiting symptoms are significantly less than systemic administration. Interventional chemotherapy has high curative effect and few side effects, and patients are willing to accept it, which broadens the treatment channels for patients with advanced ovarian cancer.
Is ovarian cancer surgery expensive? Ovarian cancer is a common female tumor, and the best treatment for patients is surgery. Because it is a complicated operation, the cost of the operation is particularly concerned. So, is ovarian cancer surgery expensive?
Regarding the price of ovarian cancer surgery, there is no numerical expression, because the price of ovarian cancer surgery is affected by many factors, the following are common influencing factors:
1, operation mode
Every patient's situation will be different, so will the surgical methods of ovarian cancer, and the price of surgery will naturally be different.
2. Hospital choice
There are many hospitals that carry out ovarian cancer surgery, and the charging standard and medical level of each hospital are different, so the choice of hospital will also affect the price of ovarian cancer surgery.
3. Regional differences
The consumption level of first-tier cities and small cities will definitely be different. The bigger the city, the higher the consumption level, and the higher the relative price of ovarian cancer surgery. This is common sense.
4, postoperative care
Postoperative care will also affect the price. Different nursing standards will definitely lead to different prices. But in any case, we should do a good job of nursing correctly to avoid falling short.