/kloc-0 was admitted to the graduate school of Peking union medical college in September, 1986, and199/kloc-0 was awarded the doctor's degree in June, 1986.
1987- 1988 studying hand surgery in beijing jishuitan hospital.
1989 was selected by the Ministry of Health to go abroad to participate in the one-year "International Dermatology Training Course" jointly organized by WHO, Japanese and Thai governments, and obtained an international diploma in dermatology, a doctor's license and a master's degree in dermatology. He is currently the director of the Scar Treatment Center of Plastic Surgery Hospital of China Academy of Medical Sciences and a member of the academic committee of the hospital. He is also a member of the trade union, the infection committee, the medical record committee, the academic committee and the vice-captain of the hospital emergency team.
He published more than 20 papers and participated in the compilation of 4 monographs on plastic surgery, translated 1 translation. Member of the Seventh Central Committee of Taiwan Democratic Self-government League, representative of the 12th People's Congress of Beijing, and member of the 10th Committee of China People's Political Consultative Conference.
Main scientific research fields:
(1) Research on parasite reproduction and physiology: Focus on the molecular characteristics and dynamics of key enzymes in the process of embryo development and egg formation of medical egg suction, as well as the molecular mechanism of enzyme action.
(2) Screening of small molecular drugs and study on their anti-pathogen mechanism: mainly screening small molecular inhibitors of key enzymes in isoprene-like synthesis pathway unique to pathogenic organisms (such as plasmodium, Toxoplasma gondii and Mycobacterium tuberculosis); At the same time, the molecular structure mechanism of small molecules inhibiting key enzymes efficiently and its molecular mechanism of resisting the proliferation of pathogens were revealed.
He presided over two special funds of Hubei Provincial Health Department and the national natural science fund 1 sub-project; Participated in 4 national natural science foundation projects, Hubei natural science foundation project 1, provincial science and technology public relations project 1, and provincial health department fund key project 1. There is 1 appraisal result, the third prize of Hubei Science and Technology Natural Science Award 1. He has published nearly 40 academic papers, including 16 papers published by SCI and more than 30 papers published by the conference.
Main academic part-time:
He is currently a member of the Academic Committee of Beijing Tropical Medicine and Parasitology Forum and a member of journal of tropical diseases and parasitology Branch of Hubei Medical Association. He is now a member of Wuhan Branch of Chinese Preventive Medicine Association, Chinese Preventive Medicine Association, Chinese Zoological Society and Korean Parasitology Society.
Teaching situation:
Undergraduate: theoretical and experimental teaching of clinical medicine, medical examination, human parasitology of preventive medicine, human parasitology and examination, pathogenic biology and other courses; Teaching of food-borne parasitic diseases, modern lifestyle and parasitic infection in general education courses in universities; Theoretical and experimental teaching of "Pathogenic Biology" in clinical English class.
Postgraduates: theoretical teaching of clinical microbiology, principles of medical bioinformatics, pathogenic biology, new progress of pathogenic biology, scientific research methods and norms, writing of medical scientific papers, medical literature information retrieval and other courses. For more than 20 years, we have been working in the front line of clinical medicine, actively training and teaching junior doctors, advanced students and graduate students. Patiently guiding clinical work and helping to solve difficult problems, he presided over the "qualitative and quantitative study of lateral thoracic vessels", which solved the problems of complex distribution, great variation and difficult selection of vascular pedicle in lateral thoracic region, and then completed the "clinical application of free lateral thoracic flap to repair soft tissue defects in face and neck" project, and diagnosed and treated many special difficult cases. Conduct teaching lectures and participate in national continuing education and postgraduate teaching tasks. He not only led the general practitioner to insist on weekly rounds, but also undertook the training and teaching tasks of graduate students, and participated in and guided the project design, experimental model, clinical guidance, literature search, graduation thesis writing and so on. As a member of the tutor group, he has helped to train 8 graduate students and 0 doctoral students/kloc-0.
In our hospital, * * * has completed more than 10000 clinical operations. He published more than 20 papers and participated in the compilation of 4 monographs on plastic surgery, translated 1 translation. MEDLINE 1996 contains two papers. He presided over and participated in more than 20 scientific research projects. One of them won the second prize of scientific and technological progress of the Ministry of Health. Cleft lip and palate, modern facial and neck plastic surgery, including integrated fashion design and surgical sculpture of eyes, eyebrows, nose, jaw and lips, facial rejuvenation and regeneration, and comprehensive treatment of facial acne scars; Body surface shaping needle liposuction; Surgical and non-surgical comprehensive treatment of various infections, burns, wounds and postoperative scars, especially good at microsurgical flap remote repair, local flap transfer repair, low-injury micro-incision multiple skin and soft tissue expander implantation repair, scar grinding; Repair of congenital cleft lip and palate, congenital torticollis and congenital syndactyly (toe); Excision, radical treatment and repair of various body surface pigmentation and tumors.
Main representative works:
1) Cai, Deng, Sylvia N.J. Moreno, Boris Streepen, Song Yongcheng. Expression, identification and inhibition of Toxoplasma gondii 1- deoxy -D- xylulose -5- phosphate reductase isomerase. Bioorganic and bioengineering. Medicinal chemistry letters 2013,23 (7): 2158-2161.
2), Diao Jiasheng, Cai (He Xian), Deng, Song Yongcheng. Anti-malaria and structural study of pyridine inhibitor containing 1- deoxyxylulose -5- phosphate reductase isomerase. ACS Pharmacochemistry Express 2013,4 (2), 278-282.
3) Pei Yongan, Guo, Jin Shanxi, Sun Yunmo, Yin Gang. Expression pattern and substrate specificity of tyrosinase from Clonorchis sinensis. International Journal of Parasitology 2013,43 (11): 891-900.
4) Pei Yongan, An Donghuan, Li Enguo, Jin Chengxi, Guo, Yin Su, Sun Yunmo, Yin Gang. Differential activation of different glutathione transferases of Clonorchis sinensis in host bile and oxidative stress response. The denial of the plo. Trop。 Dis.20 13，7(5): e22 1 1。
5) Cai, Deng, Bartlomiej G. Fryszczyn, Nicholas G. Brown, Hong Jiang, Timothy Palzkill and Song Yongcheng. Thermodynamic study on the binding of inhibitors to 1- deoxy -D- xylulose -5- phosphate reductase isomerase. ACS medicinal chemistry letter 2012,3,496-500.
6) Yuan He, Cai (co-organizer first), Ni Yonghui, Zong, Li He. SiRNA-mediated knockout of tyrosinase gene of Schistosoma japonicum in vitro. Experimental parasitology 20 12, 132: 394-402.
7) Justin L., Deng, Cai, Hong Jiang, Cheng Gang, Chen Pinhong, Dong Shuo and Song Yongcheng. Synthesis and structure-activity relationship of adenosine-containing inhibitors of histone methyltransferase DOT1L. Journal of medicinal chemistry 20 12, 55: 8066-8074.
8) Baihua He, Cai (co-organizer first), Ni Yonghui, Zong, Li He. Identification and expression of neocystatin gene from Schistosoma japonicum. Molecular and cellular probes 20 1 1, 25: 186- 193.
9) Pei Yongan, Guo, Jin Shanxi, Zou Yongjian, Yin Gang. Modular evolution of glutathione peroxidase gene in invertebrates and different biochemical characteristics of its encoded protein. BMC Evolutionary Biology 2009,6; 9: 72.
10)s-h KIM, g-b CAI (common first), y-a BAE, e-g LEE, y-s LEE and y-KONG. Oxidative stress induces two new phosphoglutathione peroxidase genes in Paragonimus westermani. Parasitology 2009, 136: 553-565.
1 1) Cai, Pei Yong 'an, Yuan He, Jiang Mingsen, Li He. Expression and identification of two tyrosinases from Schistosoma japonicum. Parasitology research 2009, 104: 60 1-609
12) Guo, Pei Yong 'an, Jin Shanxi, Sun Yunmo, Li Yunsong, Ming, Dong Soo Kim, Yin Gang. Specific expression of phospholipid hydrogen glutathione peroxidase in yolk cells of Clonorchis sinensis. International Journal of Parasitology 2008,38:1613-1623.
13) Guo, Pei Yongan, Jin Shanxi, Pei Yongguo, Dong Soo Kim, Ming, Yin Gang. A membrane-associated metalloprotease of Taenia solium structurally related to FACE- 1/Ste24p protease family. International Journal of Parasitology 2006, 36: 925-935.
14) Pei Yongan, Jin Shanxi, Guo Caibin, Li Enguo, Dong Soo Kim, Long Jinwu, Yin Gang. Differential expression of egg shell protein of Paragonimus westermani during development. International journal of parasitology 2007, 37: 295-305.
15) Jin Shanxi, Zhong Junyong, Pei Yongan, Guo, Park Yongguo, Kim Nam Joo, Guo Hanzhi, Dong Soo Kim, Yin Gang. Functional identification of neuronal nitric oxide synthase protein inhibitor of Taenia solium. Molecules and biology. Bioparasitology 2007,151:41-51.
16), Song, Bin, Li Qun, Huang Baojun, Zhang Linjie, Jiang Mingsen, Tan Jingquan. Up-regulation of CXCR3 expression in eosinophils of mice infected with Schistosoma japonicum. Immunology 2004,11:107-117.
17), Cai (correspondent),, etc. Bioinformatics analysis of glutathione peroxidase in parasitic trematode. China Journal of Zoonomatosis, 20 10/0,26 (4): 293-298.
18) Cai, Dong Huifen, Jiang Mingsen. Research progress on antioxidant enzyme family of medical trematode. China Journal of Parasitology and Parasitology.2008,26 (4): 313-317.