Experts from Wuhan Zhongyuan Otolaryngology Research Institute reminded that repeated otitis media will aggravate eardrum perforation, cause middle ear adhesion and sclerosis, and further reduce hearing. If the drug is used improperly, it will also cause the decline of inner ear nerve function and increase the difficulty of treatment. Repeated inflammation of the middle ear can lead to otitis media with osteomyelitis or cholesteatoma. When bones are eroded, it may lead to intracranial and extracranial complications such as facial paralysis, meningitis and brain abscess, and even life-threatening.