Changshu Second People's Hospital City Branch, Changshu Red Cross Hospital and Changshu Otolaryngology Hospital are all located in Fangta Street, the most prosperous area in Changshu. Its predecessor was the Sixth People's Hospital of Changshu City, which was established in 1959. Ophthalmology has been a characteristic specialty in Changshu for more than 40 years. From June 5438 to February 2003, the resources of medical institutions in Changshu were reorganized, and the former Second People's Hospital of Changshu and the Sixth People's Hospital of Changshu were optimized to form a new Second People's Hospital of Changshu. The original Sixth Hospital was renamed as Changshu Second People's Hospital Branch, Changshu Red Cross Hospital and Changshu ENT Hospital.

Chengzhong Branch is a "comprehensive" hospital featuring otolaryngology, with 130 beds. The diagnosis and treatment level of ophthalmology, otolaryngology, stomatology, cardiovascular medicine, traditional Chinese medicine, endocrinology, tumor surgery, vascular surgery, orthopedics, anorectal surgery and cosmetic plastic surgery is leading in the city.

Over the years, Chengzhong Branch has been in a leading position in the application of modern cataract extracapsular surgery, phacoemulsification, vitrectomy, excimer laser in situ keratomileusis, eye and face plastic surgery and other specialized technologies, and won two provincial scientific and technological achievement awards. The hospital was approved by Jiangsu Provincial Health Department, Jiangsu Disabled Persons' Federation and Jiangsu Disabled Persons' Rehabilitation Office as "designated hospital for cataract surgery to help the poor" and "Changshu Low Vision Rehabilitation Center in Jiangsu Province", and the Department of Stomatology was designated as "the business guidance center for establishing an advanced county (city) in the prevention and treatment of dental diseases in China".