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Male mammary gland hyperplasia, how to treat, the best method? Thank you, everyone.
Do male breasts sometimes increase? Under normal circumstances, male breasts will not develop. When the estrogen level in the body is relatively or absolutely increased due to various reasons, and the mammary epithelial cells are stimulated by estrogen too much, a very small number of men may have unilateral or bilateral mammary hypertrophy. Etiology and pathogenesis of gynecomastia Male mammary hyperplasia is called gynecomastia. It usually occurs around adolescence and old age, and the pathological manifestations are glandular duct hyperplasia without acinar hyperplasia, which can be generally divided into primary and secondary types. The primary patients are usually adolescent boys and elderly men, which are mainly caused by the temporary increase of endogenous estrogen or the decrease of androgen, and often subside spontaneously. Secondary patients are common in liver diseases, testicular diseases, adrenal diseases, thyroid diseases, diabetes, urogenital or nervous system tumors, prostate diseases or others. Reserpine, remifentanil, digitalis, chlorpromazine, etc. It can also cause breast development, which can generally subside after drug withdrawal. In addition, hermaphroditism and congenital testicular dysplasia can also lead to breast hypertrophy. Chinese medicine believes that a man's breast belongs to the kidney and his nipple belongs to the liver. If his mood is not harmonious, he will be furious and hurt his liver, which will lead to stagnation of liver qi. However, if he is depressed for a long time, he will turn into fire, burn the body fluids of his liver and kidney, damage his liver function, and have low detoxification function, so that excessive estrogen in the human body cannot be inactivated in the liver, but will act on the target organ breast, or he will be old and weak, unable to recover after a long illness, deficient kidney and liver, and unable to maintain liver wood. The disease can also occur when the breast collateral is tied, or the essence and blood can't support chong and ren, resulting in disorder of chong and ren, or exogenous pathogenic factors damage the liver, and the liver loses qi and blood, leading to blood stasis and phlegm coagulation, blocking meridians, and leading to male breast development. Clinical manifestations of male breast development The disease can be seen in all ages. About 60-80% of breast development is bilateral symmetry or asymmetry, and some are unilateral development (left side is more common than right side). Their breast development is characterized by different sizes, and asymmetrical or symmetrical bulges are often seen on both sides of the breast. Small ones can only touch the flat round nodules under the areola, with hard and tough texture, clear and tidy edges, good fluidity, no adhesion to the skin, and the masses are located in and. If an eccentric circular mass is found, other lesions should be considered. Clinically, this kind of mass is called' adenoma type', and the other part of the developed breast is diffuse hyperplasia with unclear margin, which is often fused with the surrounding breast tissue, and there is no obvious nodule under the areola. Most of them can gradually expand to the size of women's breasts. Clinically, this type is called' diffuse type', and well-developed breasts often have a feeling of swelling, tingling and jumping pain, if it is obvious. A few patients have white milky secretion after nipple extrusion, and spontaneous discharge is rare. How to treat gynecomastia If you find your breast hypertrophy, you should go to the hospital for diagnosis as soon as possible. If it is physiological or drug-induced, you don't have to be too nervous, you can subside on your own, or you can subside on your own after stopping taking the drug. If it is pathological, we should carefully find the cause and treat it in time. If active and effective treatment is given in the early stage, it can return to normal, but if it takes a long time, breast tissue hyperplasia is serious, which is irreversible and necessary. At present, there is no feasible treatment for this disease in western medicine, mainly using hormone antagonism treatment and surgical removal, but surgical removal is easy to leave scars, which not only affects the appearance but also is easy to recur. At present, it is often not used, except that it is too large, swollen and painful, and even causes mental anxiety. At the same time, drug treatment is ineffective, and patients insist on resection, otherwise surgical treatment is generally not recommended. In addition, due to the complexity of the etiology, different causes have different treatment methods for male gynecomastia. Adolescent patients in the early stage of breast development often heal themselves and generally return to normal within 6 months. Primary patients in adults and the elderly are not easy to heal themselves and should be treated actively. Secondary male breast development because it is often accompanied by other diseases; Therefore, treating the cause is an important measure. Over the years, our hospital has accumulated rich clinical experience in non-surgical treatment of this disease. In the treatment, according to the theory of traditional Chinese medicine and its different clinical manifestations, we should adjust the liver and kidney to adjust the function between hypothalamus-pituitary-testis axis, restore liver function, strengthen the inactivation of excess estrogen, promote metabolism, improve blood circulation, protect liver and kidney, rationally regulate endocrine and make the body healthy. From the pharmacological research, traditional Chinese medicine does not have many side effects of western medicine and hormone drugs, and its curative effect is also very remarkable. At the same time, the onset of this disease has a certain relationship with mood. Therefore, it is very important to adjust mood, keep happy, avoid anger and worry, and pay attention to the combination of work and rest. You should quit smoking and drinking at ordinary times, and you should not eat too much greasy and spicy food in your diet. During the illness, you should feel comfortable, have confidence in the treatment of the disease, adhere to the necessary physical exercise and functional exercise, pay attention to the local cleaning of the breast, prevent nipple and skin damage, and prevent infection. Can five men also get breast cancer? Men also get breast cancer, but it is very rare, accounting for about 1-2% of breast cancer. Compared with women, there are opposite differences in sex hormones, and androgen is dominant. Because men's breast tissue can't get the necessary estrogen stimulation, especially the breast leaves and glandular epithelium atrophy in the breast structure, men are less likely to get breast cancer. Although the possibility of male breast cancer is very small, there are still new diseases. Because of the anatomical and histological characteristics of male breast, such as small size and short lymphatic vessels in the tissue, male breast cancer is easy to metastasize, infiltrate and spread early in clinic. In addition, clinically, it is found that the curative effect of testicular resection in late stage of male breast cancer is better than that of ovarian resection in late stage of female breast cancer. Therefore, when a man finds a lump in his breast, he should seek medical treatment in time to avoid delaying diagnosis and treatment and causing adverse consequences; In addition, because gynecomastia is not only an objective manifestation of male hormone imbalance, but also an important cause of male breast cancer, it can be used as an important basis for the diagnosis of male breast cancer. In a word, gynecomastia is not only a primary disease, but also secondary to many other serious diseases, so we should be vigilant and make timely diagnosis and treatment. When acute inflammation of the breast occurs, most of them first have nipple pain, rupture or breast lump and swelling pain, and then, chills, chills and fever. The affected breast is tender, the skin is red and swollen, the skin temperature is increased, and there is a subcutaneous lump, or the skin is not red, swollen or hot, and the lump is deep and unconnected with the skin, but the pain or tenderness is heavier. In addition, there are swollen and tender lymph nodes in the ipsilateral armpit. If the treatment is not timely and appropriate, the lesion will inevitably continue to develop. The affected breast is more red and swollen, and the lump becomes soft and undulating, forming subcutaneous or superficial breast abscess. Finally, the abscess pierces outward or expands to the inner side of the breast, or the deep lump becomes bigger and softer, and the skin that was not red and swollen becomes red and swollen, the lesion scope becomes larger and larger, and the destruction of breast tissue increases. Abscess can not only pierce the skin outward, but also pierce the mammary duct inward to make the milk contain pus, and even pierce the muscles of the chest wall backwards to form a retromammary abscess. At this point, systemic symptoms are getting more and more serious. Early treatment is the only way to prevent too much damage to the breast. Generally, the following measures are taken: 1. The affected breasts stop breastfeeding and suck milk on time. 2. Hold up the affected breast: Holding up the affected breast with a bra or a pocket belt can improve the blood circulation of the breast. Blood circulation is smooth, local blood is not congested, swelling is easy to subside, and inflammation is easy to control. 3. External application: cold compress can be used locally in the early stage. If suppuration is inevitable, use hot compress instead. Three or four times a day, 30 minutes each time. It would be better if we could do it continuously. Local swelling can be coated with Chinese medicine gold powder. 4. Physiotherapy: Infrared radiation (ordinary light bulb100W is also acceptable) can promote local blood circulation, which is beneficial to the absorption and dissipation of inflammation. 5. Internal treatment: intramuscular or intravenous injection of antibacterial and anti-inflammatory drugs. Chinese medicine antler powder is taken orally twice a day, 5 grams each time, which can help digestion. 6. Incision and pus discharge: If the local area has become a suppurative drug. It is necessary to cut open and drain pus as soon as possible, and pus flow can avoid the spread of inflammation. Mastitis prevention is expensive and can be completely prevented. The key is to prevent nipple rupture and milk deposition. March 2 1, 20:46 drug treatment status: Hyperplasia of mammary glands is the most common breast disease, which can occur in women of any age after puberty, accounting for about 75% of all breast diseases. Modern medicine believes that the occurrence of mammary gland hyperplasia is related to endocrine dysfunction and ovarian dysfunction, which leads to the increase of estrogen level or activity in the body, while the decrease of progesterone level, and the imbalance between progesterone and estrogen. Therefore, western medicine mainly uses sex hormone therapy and endocrine therapy to treat this disease. Traditional Chinese medicine believes that this disease belongs to the category of "breast addiction", "breast swelling" and "tuberculosis in milk" in traditional Chinese medicine. "Emotional internal injuries, liver depression and qi stagnation; Deficiency of liver and kidney, imbalance of chong and ren; Phlegm and blood stasis are congealed, and the mammary collaterals are blocked; Yangming's stomach heat, heat hurting blood collaterals "is the pathogenesis of this disease." "Chinese medicine treatment of this disease is based on syndrome differentiation, supplemented by other curative effects. The following is a brief review of drug therapy in recent years. 1, western medicine treatment 1. 1 tamoxifen: tamoxifen is an estrogen receptor antagonist, which can competitively bind with estrogen receptors in breast tissue, block the effect of excessive estrogen on breast tissue, reduce serum low-density lipoprotein, and has a good analgesic and stagnation-relieving effect, and is superior to other drugs. It is effective for breast cancer patients with estrogen receptor positive and has been widely used in clinic. The main side effects are that it can cause menstrual cycle disorder, less menstrual flow, and return to normal after stopping taking medicine; Occasionally, gastrointestinal reactions occur, such as nausea and vomiting. 1.2 thyroid hormone preparation: the regulation of thyroid function is extremely complicated, which is mutually restricted with pituitary and hypothalamus, forming a feedback mechanism of hypothalamus ←→ pituitary ←→ thyroid axis. The thyroid gland can continuously supply free thyrotropin to the body, promote luteinization of follicles, thereby reducing the level of estrogen and continuously blocking the effect of estrogen on mammary gland hyperplasia. Chen Zhi and others reported that thyroid tablets were used to treat 106 patients with mammary gland hyperplasia, with 44 cases being markedly effective, 58 cases being effective and 4 cases being ineffective, with an effective rate of 96.2%. This product has little side effects and has clinical application value. Bromocriptine (1.3) is a long-acting activator of dopamine receptor, which acts on dopaminergic receptors on pituitary prolactin cells, inhibits the synthesis and release of prolactin, and reduces the antagonistic effect of RL on follicle stimulating hormone. Promote ovulation recovery and regulate hormone balance. Murta et al reported that 25 cases of benign breast fibrocystic hyperplasia were treated with this medicine orally, with a dose of 5 ~ 7.5 mg/d and a course of treatment of 3 months, and achieved good results. It has obvious curative effect on periodic breast pain and breast nodules. 1.4 danazol: It is a derivative of estrogen, which acts on hypothalamus, pituitary and ovary, inhibits ovarian function and reduces PRL level, thus reducing the role of PRL in promoting estrogen secretion. Von et al. used danazol to treat 59 women with extensive hyperplasia of mammary glands, ranging in age from 23 to 58. The oral dose of the drug was 100 ~ 800 mg/d, which was divided into three groups. The course of treatment is 40 ~ 774 days, which proves that the drug has a satisfactory effect on recurrent and persistent benign and extensive cystic hyperplasia of breast. This medicine has great side effects, mainly menstrual disorder and GPT increase, which will recover quickly after reduction or withdrawal. It is suitable for severe patients, non-pregnant and lactating patients whose symptoms are still not relieved after long-term treatment. Generally, it is not used as the first choice drug. 1.5 Sex hormone therapy: Androgen and progesterone can resist the effect of estrogen on breast tissue, and reduce the secretion of estrogen by the ovary by inhibiting the secretion of gonadotropin in the anterior pituitary gland, thus effectively preventing and treating breast hyperplasia, and 70% of patients can improve their symptoms after application. Li Guobin et al reported that medroxyprogesterone acetate was used to treat 30 cases of mammary gland hyperplasia, with 1 time, 2 tablets each time, 10 day as a cycle. After 3 cycles, 2 cases were cured, 8 cases were markedly effective and 12 cases were effective, with a total effective rate of 73.3%. 1.6 Other drugs: (1) Enzymes: For example, Rammer reported that 29 patients with breast diseases were treated with a hydrolytic protease, and the curative effect was satisfactory without disturbing the hormone level in the human body. (2) Vitamins: Vit-A can promote the conversion of inactive androsterone and gesterone into active androsterone and progesterone, both of which have anti-estrogen effects; Vit-E is an antioxidant, which can reduce low-density lipoprotein and increase high-density lipoprotein to make up for the deficiency of progesterone therapy. (3) Low dose iodine agent: such as 5% potassium iodide solution or compound iodine solution is also effective in treating this disease. 2. In addition to Xiaoyao Pill, Yueju Pill, Xiaojindan, Rukang Tablet, Xiao Ping Capsule and Asparagus Tablet, a large number of prescriptions, prescriptions, acupuncture, massage, cupping, umbilical application with Chinese medicine, chest protection with magnetic medicine and iontophoresis have achieved considerable results. The following is a brief overview of commonly used Chinese medicine therapies. 2. 1 Periodic treatment of traditional Chinese medicine: Run Hongyu and others prescribe drugs according to the changes of qi and blood in different stages of menstruation. In the early and middle period of menstruation, the methods of soothing the liver and relieving depression, promoting blood circulation and dredging collaterals, resolving phlegm and resolving hard mass were established, and Xiaoyao San was modified. Medicines: Bupleurum, Angelica sinensis, Radix Paeoniae Rubra, Radix Curcumae, Rhizoma Cyperi preparata, zucchini, Luffa, Radix Salviae Miltiorrhizae, Rhizoma Sparganii, sea irrigation, Gleditsia sinensis, Shā rotto Katakuri, etc. In the later period of menstruation, on the basis of nourishing liver and kidney and regulating chong and ren, the methods of regulating qi and removing blood stasis, softening and resolving hard mass were established, and Erxian decoction combined with Xiaoyao powder was added and subtracted. Medicinal materials: Rhizoma Curcumae, Radix Bupleuri, Radix Angelicae Sinensis, Radix Paeoniae Alba, Semen Cuscutae, cornu Cervi Degelatinatum, Herba Cistanches, Prunella vulgaris, Concha Ostreae, Rhizoma Curcumae, Bombyx Batryticatus, etc. For patients with qi stagnation, premenstrual breast pain is obvious, Fructus Toosendan, Pericarpium Citri Reticulatae Viride, Fructus Hordei Germinatus and Fructus Crataegi can be added. For patients with blood stasis, the breast lump is hard and stinging, and Semen Persicae, Herba Leonuri, Semen Vaccariae, Olibanum, Myrrha, Squama Manis and Hirudo can be added. Such as patients with spleen and kidney yang deficiency, breast swelling and pain before or during menstruation, codonopsis pilosula, Atractylodes macrocephala, Astragalus membranaceus, Morinda officinalis, etc. Can be added; For example, in patients with liver and kidney yin deficiency, the breast lump is hard, dull and painful. Curculigo, Epimedium and cornu Cervi Degelatinatum are removed from the prescription, and Lycium barbarum, Ligustrum lucidum, Scrophularia root, Ophiopogon japonicus and Trichosanthes root are added. 2.2 Treatment based on syndrome differentiation: According to the basic principles of soothing the liver and relieving depression, resolving phlegm and resolving hard mass, An Li et al. made their own decoction: 9g of Pericarpium Citri Reticulatae Viride, 9 g of kelp, 9 g of frankincense, 0/2g of Prunella vulgaris/KLOC-,and 65,438 g of Fritillaria thunbergii. 200 cases of liver depression and phlegm coagulation syndrome were treated, and the total effective rate was 965438 0.5%. The rest will be divided into three types: (65,438+0) liver depression and qi stagnation, and the treatment should be soothing the liver, dredging collaterals, diminishing inflammation and dispersing stagnation. Basic prescription: Bupleurum, Patrinia, Squama Manis and Oyster each 65438±02g, Rhizoma Cyperi, Rhizoma Sparganii, Pericarpium Citri Reticulatae Viride and Radix Curcumae each 65438±00g, Fructus Aurantii 6g, Rhizoma Curcumae, Luffa sponge, Semen litchi and Gynostemma pentaphyllum each 65438±05g. Coptidis Rhizoma and Gardenia Fructus are added for qi stagnation and fire; Patients with insomnia can add Semen Ziziphi Spinosae and Caulis Polygoni Multiflori. (2) Spleen deficiency and phlegm coagulation type should strengthen the spleen and dredge collaterals, reduce swelling and dissipate stagnation. Basic prescription: Radix Codonopsis, Concha Ostreae, Squama Manis, Luffa, Patrinia, Gynostemma pentaphyllum, Poria, Pinellia ternata, Rhizoma Sparganii, Pericarpium Citri Tangerinae, Atractylodis Macrocephalae, Semen Sinapis Albae, Rhizoma Curcumae, and Semen Litchi. If the hands and feet are not warm, add processed ginger and cinnamon; Colla Corii Asini and Semen Ziziphi Spinosae are added to palpitation and insomnia. (3) Kidney deficiency is out of balance, so it is advisable to tonify kidney and dredge collaterals, reduce swelling and dissipate stagnation. Basic prescription: 65,438 00 grams of Rhizoma Curculiginis, cornu Cervi Degelatinatum, Semen Cuscutae and Cortex Cinnamomi, 65,438 05 grams of Rhizoma Curcumae and Semen Litchi, and 65,438 02 grams of Concha Ostreae, Squama Manis, Luffa Fructus, Herba Epimedii, Herba Patriniae and Gynostemma pentaphyllum. Rhizoma Cibotii and Eucommiae Cortex are added for patients with lumbago; For patients with menorrhagia, ophicalcite is added; Rhizoma Polygonati and Radix Polygalae can be added for tinnitus and insomnia. Clinical observation shows that 62 cases have a cure rate of 50% and a total effective rate of 96.55%. 2.3 Prescription addition and subtraction: Huang Lizhen used Rupi decoction to add and subtract according to symptoms. The pharmaceutical composition is: green tangerine peel, dried tangerine peel, Cyperus rotundus, angelica sinensis, radix paeoniae alba, curcuma aromatica, poria cocos, white mustard seed each 12g, orange seed 15g, semen vaccariae 20g, Bombyx batryticatus 10g, and oyster 30g. For patients with severe breast pain, add 6g of frankincense, 2 g of Rhizoma Corydalis/kloc-0, and 5 g of Fructus Toosendan/kloc-0; For those with persistent breast lumps, 9 grams of Sparganium, 0/0 gram of Rhizoma Curcumae/KLOC, 20 grams of Shā rotto Katakuri and 30 grams of seaweed; Be added; Herba Epimedii 12g, Herba Cistanches 15g, and Colla cornus Cervi 10g can be added for patients with kidney deficiency. After 1 10 treatment, 49 cases were cured, 54 cases were improved and 7 cases were ineffective. The total effective rate was 93.63%. He Zengfu treated 56 cases of hyperplasia of mammary glands with Chaihu Shugan Decoction, with turtle shell 20g, salvia miltiorrhiza 15g, astragalus root 20g, pseudostellaria root 20g, fried corydalis yanhusuo 15g and chrysanthemum 30g for patients with breast enlargement. Clinical treatment showed that 29 cases were cured, 4 cases were markedly effective/kloc-0, and 65438+ cases were effective. Chen Aifen used Xuefu Zhuyu Decoction to treat 50 cases of mammary gland hyperplasia, of which 0 cases were cured, 6 cases were effective and 3 cases were ineffective. Basic prescription: peach kernel, safflower, angelica, red peony root, chuanxiong rhizome, moutan bark, Bupleurum root, bitter orange, platycodon grandiflorum, roasted licorice root, pangolin scales and Cyperus tuber. Low back pain plus dipsacus and mistletoe; Stir-fried gardenia dandelion with blood heat; Radix Codonopsis and Radix Astragali are added for qi deficiency; Prunella vulgaris and orange pit are added to scleredema, and pangolin scales are reused; If the pain is severe, Rhizoma Corydalis and Fructus Toosendan can be added. 2.4 Self-made preparations: In addition to the commonly used Chinese patent medicines, there are many Chinese patent medicines made in various places for the treatment of mammary gland hyperplasia, all of which have achieved good results. 75 cases of mammary gland hyperplasia were treated with Runing Granule developed by Lu Deming et al. The clinical cure rate is 32%, and the total effective rate is 93.33%. The Jianru Juanpi Capsule developed by Wu Xia et al. is composed of Pericarpium Citri Reticulatae Viride, Fructus Trichosanthis, Squama Manis, Semen Persicae, Bulbus Fritillariae Cirrhosae, Scorpio, Scolopendra, and Red Moxibustion, 7 capsules each time, 1 time every night, and 1 course of treatment for 30 days. 65,438+055 cases were treated, 96 cases were cured and 29 cases were markedly effective, with a total effective rate of 94.438+09. 2.5 External treatment: Song Aili and others put forward the treatment principles of warming channels and promoting blood circulation, regulating qi and relieving pain, dispersing stagnation and reducing swelling. Rhizoma corydalis, Carthami Flos, Semen Vaccariae, Borneolum Syntheticum and Moschus are made into ointment by modern preparation method. The treatment adopt that external treatment method of combining local breast medication with skin and acupoint massage, so that the medicine can directly act on the affect part, improve the blood supply of the breast through transdermal absorption and stimulation of meridians and acupoints, have the effects of relieve pain, reducing swelling and resolving hard mass, and regulate endocrine reflexively. 200 cases were clinically treated, 36 cases were cured, and the total effective rate was 95.5%. Gu Baoxiang and others used computer infrared comprehensive therapeutic instrument and iontophoresis of traditional Chinese medicine. According to the different etiology and pathology of the disease, they selected Bupleurum, Angelica sinensis, seaweed, kelp, sparganium, zedoary, Pinellia ternata, orange pit, white mustard seed, cornu Cervi degelatinatum and dandelion, and prepared three different series prescriptions of iontophoresis of traditional Chinese medicine, 1 time every day for 30 minutes, and 10 day was a course of treatment. 2.6 Internal and external treatment: Zhu Guigu and others take Shuang Hu decoction for 20 days a week after purification, mix it with warm water and egg white for external use, and apply it to the affected area once every two days. 10 is a course of treatment. Treatment 104 cases, 59 cases were cured, and the total effective rate was 95.2%. Li Shijin et al. used self-made Shugan Sanjie decoction to add and subtract, and added Chuanxiong and peach kernel for less menstrual flow; Black meridian with blood clots, go to Kunbu and add oysters, passepartout and orange stones; The lump is tough and hard, and Rhizoma Sparganii and Rhizoma Curcumae are added. 760 cases of mammary gland hyperplasia were treated with external pads, and 463 cases were cured. The total effective rate was 96.65438 0%. 3. Treating Jiang Jing with integrated traditional Chinese and western medicine. Xiaoyao Pill combined with vitamin E was used to treat this disease, and 9g Xiaoyao Pill and Vit-E50mg were taken orally, three times a day, and 20 days was a course of treatment. If the pain is relieved and the lump subsides, continue to take Xiaoyao Pill for a week to consolidate the curative effect. Once a month, 86 cases are treated, 56 cases are cured and 20 cases are improved, and the total effective rate is 85.7%. Wang et al. adopted the following scheme: (1) oral administration of Rupi decoction, daily 1 dose after menstruation, and monthly 15 dose; (2) Dried and fresh Hedyotis diffusa 10g, taken with boiled water; (3) Oral tamoxifen twice a day,100 mg; Every time; Aspartate tablets, 25 mg, twice a day. 84 cases of mammary gland hyperplasia were treated with combination of traditional Chinese and western medicine, and 44 cases were cured, with a total effective rate of 96.4%. 4. Conclusion 4. 1 Benign proliferative diseases of breast are common and frequent, which can be stopped at a certain stage, relieved or cured after several months or years of onset, or gradually developed into cancer in the middle and late stages. Lobular hyperplasia, cystic hyperplasia, adenopathy, fibrosis, etc. It is different stages of hyperplasia and can also appear in the same tissue. All kinds of mammary gland hyperplasia can be accompanied by epithelial hyperplasia of different degrees. Breast cancer comes from developing atypical epithelial hyperplasia. It is reported that the canceration rate of breast cystic hyperplasia is 2-4%, and this risk can last for 30 years after the diagnosis of breast cystic disease. Therefore, active treatment of benign hyperplasia of mammary glands is of great significance to improve women's health and reduce the rate of malignant transformation. 4.2 The application of sex hormones and endocrine therapy in the treatment of this disease, although the curative effect is good, has great side effects, especially sex hormones, which may further interfere with the balance of hormones in the human body and increase the possibility of cancer. Therefore, it is generally not used as a routine drug, and it is only considered when the symptoms are serious. For those with malignant tendency of severe hyperplasia, surgical treatment should be taken. 4.3 Treating this disease with traditional Chinese medicine has reliable curative effect and almost no side effects. Commonly used drugs include Bupleurum, Rhizoma Cyperi, Pericarpium Citri Tangerinae, Semen Litchi, Fructus Aurantii Immaturus, Semen Vaccariae, and Prunella vulgaris. Angelica, Radix Paeoniae Rubra, Semen Persicae, Radix Salviae Miltiorrhizae, etc. Promoting blood circulation and removing blood stasis; Pinellia ternata, Fritillaria thunbergii, oyster, seaweed, kelp, zedoary, pangolin, Shā rotto Katakuri, etc. Curculigo, Xianling brand, antler cream, dodder, etc. Although traditional Chinese medicine has practical advantages in treating the disease, it is of great significance to develop a new dosage form that is convenient to take and quick to take effect as soon as possible because of its long course of treatment and mostly decoction. 4.4 Breast hyperplasia is closely related to mental state, and it is also a psychosomatic disease in medical psychology. In addition to drug treatment, the treatment should adopt dredging therapy.

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